Polymeric solid dispersion Vs co-amorphous technology: A critical comparison

SKA Vullendula, AR Nair, DL Yarlagadda… - Journal of Drug Delivery …, 2022 - Elsevier
Historically, amorphous solid dispersion technology with polymeric carriers has been
employed to stabilize high-energy amorphous phases of poorly water-soluble drug …

Stoichiometrically governed curcumin solid dispersion and its cytotoxic evaluation on colorectal adenocarcinoma cells

JMM Mohamed, A Alqahtani, F Ahmad… - Drug design …, 2020 - Taylor & Francis
Background Colorectal cancer (CRC) is the third most commonly occurring cancer in men
and the second most commonly occurring cancer in women. Curcumin (CMN) is obtained …

Formulation, Characterization, and in Vivo Evaluation of Celecoxib-PVP Solid Dispersion Nanoparticles Using Supercritical Antisolvent Process

ES Ha, GH Choo, IH Baek, MS Kim - Molecules, 2014 - mdpi.com
The aim of this study was to develop celecoxib-polyvinylpyrrolidone (PVP) solid dispersion
nanoparticles with and without surfactant using the supercritical antisolvent (SAS) process …

Fabrication and evaluation of valsartan–polymer–surfactant composite nanoparticles by using the supercritical antisolvent process

MS Kim, I Baek - International journal of nanomedicine, 2014 - Taylor & Francis
The aim of this study was to fabricate valsartan composite nanoparticles by using the
supercritical antisolvent (SAS) process, and to evaluate the correlation between in vitro …

Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

ES Ha, JS Kim, I Baek, JW Yoo, Y Jung… - Drug Design …, 2015 - Taylor & Francis
In the present study, solid dispersion nanoparticles with a hydrophilic polymer and surfactant
were developed using the supercritical antisolvent (SAS) process to improve the dissolution …

[PDF][PDF] The Effects of Different Solubilizing Agents on the Transport and Pharmacokinetic Profiles of Indomethacin: in vitro and in vivo Approach

A HAMID, SH KHALID - Sains Malaysiana, 2024 - researchgate.net
The poor water solubility of new chemical entities (NCEs) discovered in pharmaceutical
screening programs hampers their development and limits effective treatment delivery …

Development and evaluation of self-nanoemulsifying drug delivery systems for oral delivery of indomethacin

BNA Aldosari - 2018 - discovery.ucl.ac.uk
In this study, indomethacin-loaded self-nanoemulsifying drug delivery systems (SNEDDS)
were developed in liquid, solid and carrier-mediated formulations in order to improve the …

The Effects of Different Solubilizing Agents on the Transport and Pharmacokinetic Profiles of Indomethacin: in vitro and in vivo Approach (Kesan Agen Pelarut Berbeza …

SA ZAINUDDIN, AL AB HAMID, AI RAFANDI… - Sains …, 2024 - ukm.edu.my
The poor water solubility of new chemical entities (NCEs) discovered in pharmaceutical
screening programs hampers their development and limits effective treatment delivery …

[PDF][PDF] Разработка лекарственных форм метронидазола с применением твёрдых дисперсий

ИИ Краснюк - 2023 - sechenov.ru
На терапевтический эффект активной фармацевтической субстанции (АФС) влияют
технология и вид лекарственной формы (ЛФ). Разработка новых лекарственных …

[PDF][PDF] Synthesis, characterization and in vivo assessment of dexibuprofen-eudragit solid dispersion nanoparticles with supercritical antisolvent technique

M AKHLAQ, S BAKHSH, M SAFDAR… - … American Journal of …, 2016 - latamjpharm.org
The current study shows drug/polymer nanoparticles can raise the ratio and amount of oral
absorption of a low solubility and high-permeability drug. Dexibuprofen-Eudragit solid …