Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9
A primary objective in malaria vaccine design is the generation of high-quality antibody
responses against the circumsporozoite protein of the malaria parasite, Plasmodium …
responses against the circumsporozoite protein of the malaria parasite, Plasmodium …
Novel antibody competition binding assay identifies distinct serological profiles associated with protection
JS Bolton, RS MacGill, E Locke, JA Regules… - Frontiers in …, 2023 - frontiersin.org
Introduction Pre-erythrocytic malaria vaccines hold the promise of inducing sterile protection
thereby preventing the morbidity and mortality associated with Plasmodium infection. The …
thereby preventing the morbidity and mortality associated with Plasmodium infection. The …
High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire
Antibodies targeting the human malaria parasite Plasmodium falciparum circumsporozoite
protein (PfCSP) can prevent infection and disease. PfCSP contains multiple central …
protein (PfCSP) can prevent infection and disease. PfCSP contains multiple central …