Meningitis is an inflammation of the protective membranes called meninges and fluid
adjacent the brain and spinal cord. The inflammatory progression expands all through …

Quality by design (QbD) can also contribute to design, manufacturing, and producing highly
finished goods. To better explain the manufacturing processes, the FDA focused QbD in the …

Paclitaxel (PTX) is an essential anticancer drug from the biopharmaceutical classification
system (BCS) class IV. Unfortunately, PTX has some drawbacks including low solubility, cell …

Aims Silibinin offers potential anticancer effect with less aqueous solubility and high
permeability. The present study aimed to develop biocompatible magnetic-core-based …

Central composite designs (CCD) are very efficient response surface designs which provide
information exclusively on the effect of experiment variables and overall experimental error …

Silibinin shows multi-applications and therapeutic activities such as anticancer, antioxidant,
hypocholesterolemic, cardioprotective, neuroprotective and hepatoprotective but exhibits …

Traditional bonded dust suppressants have high viscosity, insufficient fluidity and poor
permeability problems, which is adverse to the formation of a continuous and stable …

The production of nanoparticles is a very promising approach for improving the delivery of
hydrophobic drugs due to their unique properties and advantages. Even though such …

Quality is the most important and necessary attribute for pharmaceutical product
development, and it has become the focus of regulatory bodies in order to approve safe …

Blood brain barrier is considered as the physiological barrier that restricts the entry of
molecules into the central nervous system. The drug delivery mechanisms across blood …