Computational strategies for a system-level understanding of metabolism

P Cazzaniga, C Damiani, D Besozzi, R Colombo… - Metabolites, 2014 - mdpi.com
Cell metabolism is the biochemical machinery that provides energy and building blocks to
sustain life. Understanding its fine regulation is of pivotal relevance in several fields, from …

Exploring the mechanisms underlying the phenotype of MCAD deficiency with Systems Medicine: from computational model to mice to man

AC Martines - 2019 - research.rug.nl
The deficiency of the enzyme Medium-Chain Acyl-CoA Dehydrogenase (MCAD) is the most
prevalent inborn error of mitochondrial fatty acid oxidation (mFAO). During fasting or high …

[PDF][PDF] Exploring the mechanisms underlying the phenotype of MCAD deficiency with Systems Medicine

AC Martines - research.rug.nl
Cover design: Studio JNNFR Cover meaning: The cover is in honor of all who contribute
passionately to gain more insight into MCAD deficiency to help all MCADǦdeficient …

[PDF][PDF] Computational Strategies for a System-Level Understanding of Metabolism

MS Nobile, D Gaglio, D Pescini, S Molinari, G Mauri… - academia.edu
Cell metabolism is the biochemical machinery that provides energy and building blocks to
sustain life. Understanding its fine regulation is of pivotal relevance in several fields, from …

A Computational Approach for Multi-Level Biological Complex Systems Analysis

R Colombo - 2015 - boa.unimib.it
Due to their intrinsic nature, biological entities are universally considered as complex
systems. Over years, many different computational methods pertaining to the Systems …