Skeletal muscle contraction relies on both high-fidelity calcium (Ca2+) signals and robust
capacity for adenosine triphosphate (ATP) generation. Ca2+ release units (CRUs) are highly …

Abstract Store-operated Ca 2+ entry (SOCE) is a Ca 2+ entry mechanism activated by
depletion of intracellular Ca 2+ stores. In skeletal muscle, SOCE is mediated by an …

Abstract Store-operated Ca2+ entry (SOCE), a ubiquitous mechanism that allows recovery of
Ca2+ ions from the extracellular space, has been proposed to limit fatigue during repetitive …

For physiological processes in the vital organs of eutherian mammals to function, it is
important to maintain constant core body temperature at∼ 37° C. Mammals generate heat …

Calcium release units (CRUs) and mitochondria control myoplasmic [Ca 2+] levels and ATP
production in muscle, respectively. We recently reported that these two organelles are …

Store-operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ influx mechanism triggered by
depletion of Ca2+ stores from the endoplasmic/sarcoplasmic reticulum (ER/SR). We recently …

Calsequestrin (CASQ) was discovered in rabbit skeletal muscle tissues in 1971 and has
been considered simply a passive Ca2+-buffering protein in the sarcoplasmic reticulum (SR) …

Calsequestrin (CASQ) is the most abundant Ca 2+ binding protein localized in the
sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. The genome of vertebrates …

Duchenne muscular dystrophy (DMD), an X-linked disorder caused by loss-of-function
mutations in the dystrophin gene, is characterized by progressive muscle degeneration and …

Calsequestrin is the major Ca 2+ binding protein in the sarcoplasmic reticulum (SR), serves
as the main Ca 2+ storage and buffering protein and is an important regulator of Ca 2+ …