Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid
cells, have gained increasing attention for their role in the fine tuning of both innate and …

Dendritic cells (DCs) are well-established as major players in the regulation of immune
responses. They either induce inflammatory or tolerogenic responses, depending on the DC …

Macrophages are integral to the pathogenesis of atherosclerosis, but the contribution of
distinct macrophage subsets to disease remains poorly defined. Using single cell …

The gut microbiome plays a pivotal role in maintaining human health, with numerous studies
demonstrating that alterations in microbial compositions can significantly affect the …

Pathologic roles of innate immunity in neurologic disorders are well described, but their
beneficial aspects are less understood. Dectin-1, a C-type lectin receptor (CLR), is largely …

Dendritic cell immunoreceptor (DCIR; Clec4a2), a member of the C-type lectin receptor
family, plays important roles in homeostasis of the immune and bone systems. However, the …

Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs),
which play a pivotal role in inducing either inflammatory or tolerogenic response based on …

Immune response against pathogens is a tightly regulated process that must ensure
microbial control while preserving integrity of the infected organs. Tuberculosis (TB) is a …

Abstract Development and progression of malignancies are accompanied and influenced by
alterations in the surrounding immune microenvironment. Understanding the cellular and …

Inflammation, demyelination, glial activation, and oxidative damage are the most
pathological hallmarks of multiple sclerosis (MS). Piperine, a main bioactive alkaloid of black …