A comprehensive overview on myositis-specific antibodies: new and old biomarkers in idiopathic inflammatory myopathy

M Satoh, S Tanaka, A Ceribelli, SJ Calise… - Clinical reviews in …, 2017 - Springer
Autoantibodies specific for idiopathic inflammatory myopathy (myositis-specific
autoantibodies (MSAs)) are clinically useful biomarkers to help the diagnosis of …

Aminoacyl-tRNA synthetases: on anti-synthetase syndrome and beyond

AS Galindo-Feria, A Notarnicola, IE Lundberg… - Frontiers in …, 2022 - frontiersin.org
Anti-synthetase syndrome (ASSD) is an autoimmune disease characterized by the presence
of autoantibodies targeting one of several aminoacyl t-RNA synthetases (aaRSs) along with …

Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: heterogeneity within the syndrome

Y Hamaguchi, M Fujimoto, T Matsushita, K Kaji… - PloS one, 2013 - journals.plos.org
Objective To identify similarities and differences in the clinical features of adult Japanese
patients with individual anti-aminoacyl-tRNA synthetase antibodies (anti-ARS Abs). Methods …

A longitudinal cohort study of the anti-synthetase syndrome: increased severity of interstitial lung disease in black patients and patients with anti-PL7 and anti-PL12 …

I Pinal-Fernandez, M Casal-Dominguez… - …, 2017 - academic.oup.com
Objective. The aim was to study the prevalence, rate of appearance and severity of clinical
features in patients with different anti-synthetase syndrome (ASyS) autoantibodies. Methods …

Diagnosis and treatment of connective tissue disease-associated interstitial lung disease

R Vij, ME Strek - Chest, 2013 - Elsevier
Interstitial lung disease (ILD) is one of the most serious pulmonary complications associated
with connective tissue diseases (CTDs), resulting in significant morbidity and mortality …

An overview of polymyositis and dermatomyositis

AR Findlay, NA Goyal, T Mozaffar - Muscle & nerve, 2015 - Wiley Online Library
Polymyositis and dermatomyositis are inflammatory myopathies that differ in their clinical
features, histopathology, response to treatment, and prognosis. Although their clinical …

Idiopathic inflammatory myopathies and the anti-synthetase syndrome: a comprehensive review

M Mahler, FW Miller, MJ Fritzler - Autoimmunity reviews, 2014 - Elsevier
Autoantibodies are a hallmark in the diagnosis of many systemic autoimmune rheumatic
diseases (SARD) including idiopathic inflammatory myopathies (IIM). Based on their …

Myositis-related interstitial lung disease and antisynthetase syndrome

J Solomon, JJ Swigris, KK Brown - Jornal brasileiro de pneumologia, 2011 - SciELO Brasil
In patients with myositis, the lung is commonly involved, and the presence of anti-aminoacyl-
tRNA synthetase (anti-ARS) antibodies marks the presence or predicts the development of …

Patients with non-Jo-1 anti-tRNA-synthetase autoantibodies have worse survival than Jo-1 positive patients

R Aggarwal, E Cassidy, N Fertig, DC Koontz… - Annals of the …, 2014 - ard.bmj.com
Objective To compare the cumulative survival and event free survival in patients with Jo-1
versus non-Jo-1 anti-tRNA synthetase autoantibodies (anti-synAb). Methods Anti-synAb …

Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity

B Hervier, H Devilliers, R Stanciu, A Meyer… - Autoimmunity …, 2012 - Elsevier
The clinical phenotype and evolution of antisynthetase syndrome (ASS) are heterogeneous.
This study was therefore undertaken to identify subgroups of ASS patients with similar …