Lamellarins and related pyrrole-derived alkaloids from marine organisms

H Fan, J Peng, MT Hamann, JF Hu - Chemical reviews, 2008 - ACS Publications
Marine organisms have proven to be rich sources of unique alkaloids. In earlier surveys we
comprehensively reviewed several intriguing groups of marine alkaloids, including the …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2004 - pubs.rsc.org
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …

Lamellarins, from A to Z: a family of anticancer marine pyrrole alkaloids

C Bailly - Current Medicinal Chemistry-Anti-Cancer Agents, 2004 - ingentaconnect.com
The lamellarins form a group of more than 30 polyaromatic pyrrole alkaloids, isolated from
diverse marine organisms, mainly but not exclusively ascidians and sponges. These …

Active methylenes in the synthesis of a pyrrole motif: An imperative structural unit of pharmaceuticals, natural products and optoelectronic materials

R Khajuria, S Dham, KK Kapoor - RSC advances, 2016 - pubs.rsc.org
Pyrrole is one of the most important azaheterocycles, due to its wide range of applications in
pharmaceuticals and optoelectronic materials, coupled with its utility as an intermediate in …

[PDF][PDF] Synthesis and biological activity of lamellarin alkaloids: an overview

M Iwao, T Fukuda, F Ishibashi - Heterocycles, 2011 - nagasaki-u.repo.nii.ac.jp
Lamellarins are natural products isolated from marine invertebrates having a unique
heterocyclic ring system. Many of these natural products exhibit potentially useful biological …

Lamellarin alkaloids: Isolation, synthesis, and biological activity

T Fukuda, F Ishibashi, M Iwao - The Alkaloids: Chemistry and Biology, 2020 - Elsevier
Lamellarins are marine alkaloids containing fused 14-phenyl-6H-[1] benzopyrano [4′, 3′:
4, 5] pyrrolo [2, 1-a] isoquinoline or non-fused 3, 4-diarylpyrrole-2-carboxylate ring systems …

Anticancer alkaloid lamellarins inhibit protein kinases

D Baunbæk, N Trinkler, Y Ferandin, O Lozach… - Marine Drugs, 2008 - mdpi.com
Lamellarins, a family of hexacyclic pyrrole alkaloids originally isolated from marine
invertebrates, display promising anti-tumor activity. They induce apoptotic cell death through …

Synthetic approaches to the lamellarins—A comprehensive review

D Imbri, J Tauber, T Opatz - Marine drugs, 2014 - mdpi.com
The present review discusses the known synthetic routes to the lamellarin alkaloids
published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins …

Total synthesis of lamellarins D, L, and N

N Fujikawa, T Ohta, T Yamaguchi, T Fukuda… - Tetrahedron, 2006 - Elsevier
Total synthesis of cytotoxic marine alkaloids, lamellarins D, L, and N, has been achieved by
using Hinsberg-type pyrrole synthesis and palladium-catalyzed Suzuki–Miyaura coupling of …

[HTML][HTML] An overview on the synthesis of lamellarins and related compounds with biological interest

VPM Mitsiou, AMN Antonaki, MD Douka, KE Litinas - Molecules, 2024 - mdpi.com
Lamellarins are natural products with a [3, 4]-fused pyrrolocoumarin skeleton possessing
interesting biological properties. More than 70 members have been isolated from diverse …