The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Biomolecular markers of recurrent implantation failure—A review

AE Mrozikiewicz, M Ożarowski… - International Journal of …, 2021 - mdpi.com
Currently, infertility affects 8–12% of reproductive age couples worldwide, a problem that
also affects women suffering from recurrent implantation failure (RIF). RIF is a complex …

[HTML][HTML] Changes in the immune response against SARS-CoV-2 in individuals with severe COVID-19 treated with high dose of vitamin D

M Torres, G Casado, L Vigón, S Rodríguez-Mora… - Biomedicine & …, 2022 - Elsevier
Main cause of severe illness and death in COVID-19 patients appears to be an excessive
but ineffectual inflammatory immune response that may cause severe acute respiratory …

[HTML][HTML] Immunologic insights in recurrent spontaneous abortion: Molecular mechanisms and therapeutic interventions

D Guan, W Sun, M Gao, Z Chen, X Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Recurrent spontaneous abortion refers to the occurrence of two or more spontaneous
abortions before or during the early stages of pregnancy. The immune system plays a crucial …

Pharmacological and non-pharmacological interventions for improving endometrial receptivity in infertile patients with polycystic ovary syndrome: a comprehensive …

S Palomba, F Costanzi, D Caserta… - Reproductive BioMedicine …, 2024 - Elsevier
Direct and indirect evidence suggest that the endometrial receptivity may play a crucial role
in the reduced fertility rate of women with polycystic ovary syndrome (PCOS). Various …

Assisted reproductive technology and disease management in infertile women with multiple sclerosis

M Sparaco, L Carbone, D Landi, Y Ingrasciotta… - CNS drugs, 2023 - Springer
Multiple sclerosis (MS) predominantly affects women of fertile age. Various aspects of MS
could impact on fertility, such as sexual dysfunction, endocrine alterations, autoimmune …

母胎界面免疫微环境异常致复发性流产研究进展.

苏丹娜, 刁瑞英, 佘加杰, 帅领, 郭艳… - Journal of …, 2023 - search.ebscohost.com
母体对胚胎识别及免疫耐受的建立是妊娠的必要条件. 母胎界面免疫耐受的本质是胚胎滋养层
细胞, 蜕膜基质细胞和蜕膜免疫细胞共同参与母-胎对话的过程, 促进母胎界面免疫微环境的转化 …

Neu5Gc regulates decidual macrophages leading to abnormal embryo implantation

W Yue, Z Huiling, L Yuxin, W Ling, G Feng, L Qicai - Genes & Immunity, 2024 - nature.com
Repeated implantation failure (RIF) is one of the most prominent problems in the field of
assisted reproduction. Neu5Gc on the surface of decidual macrophages (dMΦ) leads to …

Decreased expression of SEMA4D in recurrent implantation failure induces reduction of trophoblast invasion and migration via the Met/PI3K/Akt pathway

X Chen, L Qi, C Zhao, J Xue, M Chen, L Diao… - Journal of Reproductive …, 2022 - Elsevier
Recurrent implantation failure (RIF) associated with impaired endometrial receptivity and
other factors. Disease-specific therapy has yet to be developed due to the lack of …

Exploring Natural Killer Cell Testing in Embryo Implantation and Reproductive Failure: An Overview of Techniques and Controversies

JP Gothe, AC de Mattos, CF Silveira… - Reproductive …, 2024 - Springer
The blastocyst nidation is the most crucial stage to a successful pregnancy, as the white
cells work to promote a favorable endometrial microenvironment for this process …