Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology
SJ Kaar, S Natesan, R Mccutcheon, OD Howes - Neuropharmacology, 2020 - Elsevier
Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …
disorders but are ineffective for some patients and associated with side-effects and …
Clozapine's multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms …
A de Bartolomeis, L Vellucci, A Barone… - Pharmacology & …, 2022 - Elsevier
Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …
Understanding the effects of antipsychotics on appetite control
S Mukherjee, S Skrede, E Milbank… - Frontiers in …, 2022 - frontiersin.org
Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and
other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so …
other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so …
Comparative tolerability of dopamine D2/3 receptor partial agonists for schizophrenia
Aripiprazole, brexpiprazole and cariprazine differ from all other second-generation
antipsychotics due to partial agonism at the dopamine D2 and D3 receptors. In contrast to …
antipsychotics due to partial agonism at the dopamine D2 and D3 receptors. In contrast to …
Naringin treatment improved main clozapine‐induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis
Schizophrenia is one of the major neuropsychiatric disorders affecting people worldwide.
Unfortunately, currently available antipsychotic medications possess several side effects …
Unfortunately, currently available antipsychotic medications possess several side effects …
A comparison of the metabolic side-effects of the second-generation antipsychotic drugs risperidone and paliperidone in animal models
HN Boyda, RM Procyshyn, L Tse, JWY Yuen… - PLoS …, 2021 - journals.plos.org
Background The second generation antipsychotic drugs represent the most common form of
pharmacotherapy for schizophrenia disorders. It is now well established that most of the …
pharmacotherapy for schizophrenia disorders. It is now well established that most of the …
Etiology and treatment approach for visual hallucinations in PD dementia
Y Asahara, T Mukai, M Suda… - Dementia in Parkinson's …, 2022 - books.google.com
Visual hallucinations are a common symptom of Parkinson's disease dementia. These can
cause delusions and violent behaviors that can be significant burdens on patients and …
cause delusions and violent behaviors that can be significant burdens on patients and …
Manejo farmacológico de la hiperglucemia asociada a antipsicóticos atípicos en pacientes diabéticos con esquizofrenia: una revisión sistemática
ML Galarza Torres, CA González Molineros - 2022 - dspace.ucuenca.edu.ec
Background: Diabetes mellitus represents one of the leading causes of death worldwide,
related to various factors: genetics, environmental, inappropriate lifestyle and adverse …
related to various factors: genetics, environmental, inappropriate lifestyle and adverse …