Stem cell transplantation with rehabilitation therapy presents an effective stroke treatment.
Here, we discuss current breakthroughs in stem cell research along with rehabilitation …

Stem cell therapy is a promising and rapidly advancing treatment strategy for a multitude of
neurologic disorders. Yet, while early phase clinical trials are being pursued in many …

ATP-sensitive potassium channels (K ATP channels), a group of vital channels that link the
electrical activity of the cell membrane with cell metabolism, were discovered on the …

Transplantation of neural stem cells (NSCs) has been proposed as an alternative novel
therapy to replace damaged neural circuitry after ischemic stroke onset. Nonetheless, albeit …

Introduction Ischemic stroke remains a major cause of disability and death worldwide. The
density and the spatial distribution of the primary motor (M1) cortical neurons are important …

Unlike central nervous system injuries, peripheral nerve injuries (PNIs) are often
characterized by more or less successful axonal regeneration. However, structural and …

This review summarizes recent advances in understanding the role of the nitric oxide (NO)
and cyclic GMP (cGMP) pathway in stem cells. The levels of expression of various …

Nicorandil is a dual mechanism anti-anginal agent that acts as a nitric oxide (NO) donor and
a potassium (K+) channel opener. Recent studies have evaluated the effect of nicorandil on …

Preconditioning (PC) affords the most potent cytoprotective effects ever known in the
physiological system. Since the publication of the first report that preconditioning by cyclical …

Background and purpose Cognitive impairment is a prevalent adverse consequence of
traumatic brain injury (TBI). The neuroprotective effects of nicorandil (N‐(2‐hydroxyethyl) …