Diabetes has been a worldwide healthcare problem for many years. Current methods of
treating diabetes are still largely directed at symptoms, aiming to control the manifestations …

Aging increases the susceptibility to a diverse set of diseases and disorders, including
neurodegeneration, cancer, diabetes, and arthritis. Natural compounds are currently being …

Emerging spatial profiling technology has enabled high-plex molecular profiling in biological
tissues, preserving the spatial and morphological context of gene expression. Here, we …

Preventing islet β‐cells death is crucial for treating type 2 diabetes mellitus (T2DM).
Currently, clinical drugs are being developed to improve the quality of T2DM care and self …

Background Diabetes is a disease affecting over 500 million people globally due to insulin
insufficiency or insensitivity. For individuals with type 1 diabetes, pancreatic islet …

Islet organoids open up new strategies for diabetes treatment and pancreatic tissue
engineering. Digital light processing (DLP) bioprinting has been extensively applied to the …

Abstract Background Pancreatic neuroendocrine neoplasms (PanNENs) fall into two
subclasses: the well-differentiated, low-to high-grade pancreatic neuroendocrine tumors …

Canine mesenchymal stem cells (cMSCs) have potential applications for regenerative
therapy, including the generation of insulin-producing cells (IPCs) for studying and treating …

Maturity-onset diabetes of the young (MODY) represents the most frequent form of
monogenic diabetes mellitus (DM), currently classified in 14 distinct subtypes according to …

Human pluripotent stem cell (hPSC)-derived pancreatic progenitors (PPs) can be
differentiated into beta-like cells in vitro and in vivo and therefore have therapeutic potential …