Simple Summary Here, we summarize what is known about the non-replication roles of MCM helicase, best known for its ability to unwind double-stranded DNA templates during …
S Korsak, K Banecki, D Plewczynski - Computational and Structural …, 2024 - Elsevier
Motivation: We present a user-friendly 3D chromatin simulation model for the human genome based on OpenMM, addressing the challenges posed by existing models with use …
The connection between the patterns observed in 3C-type experiments and the modeling of polymers remains unresolved. This paper presents a simulation pipeline that generates …
Vertebrate Pattern Formation, Volume 159 in the Current Topics in Developmental Biology series, highlights advances in the field, with this volume presenting interesting chapters on …
The computational modeling of chromatin structure is highly complex and challenging due to the hierarchical organization of chromatin, which reflects its diverse biophysical principles …
J Mañes-García, R Marco-Ferreres… - Current Topics in …, 2024 - europepmc.org
Transcriptional regulation plays a pivotal role in orchestrating the intricate genetic programs governing embryonic development. The expression of developmental genes relies on the …