To date, the delivery of signaling molecules for bone regeneration has focused primarily on
factors that directly affect the bone formation pathways (osteoinduction) or that serve to …

There is a growing socio-economic need for effective strategies to repair damaged bone
resulting from disease, trauma and surgical intervention. Bone tissue engineering has …

Angiogenesis is critical for successful bone repair, and interestingly, miR-210 and miR-16
possess counter-active targets involved in both angiogenesis and osteogenesis: miR-210 …

Many approaches have been made toward the development of scaffolds with good
biocompatibility and appreciable physicochemical properties to facilitate stem cell adhesion …

Injectable in situ crosslinkable gels are highly desirable clinically as they can be introduced
into a body via a minimally invasive manner using endoscopic or percutaneous procedures …

Bone is a vascularized and connective tissue. The cortical bone is the main part responsible
for the support and protection of the remaining systems and organs of the body. The …

The potential of growth factors to stimulate tissue healing through the enhancement of cell
proliferation, migration, and differentiation is undeniable. However, critical parameters on …

Inspired by the physiological events of the “wound healing cascade”, the integration of
biomaterials and growth factors is generally accepted as an emerging and powerful strategy …

The successful clinical outcome of the implanted tissue-engineered bone is dependent on
the establishment of a functional vascular network. A gene-enhanced tissue engineering …

Carbon dots are a new kind of nanomaterial which has great potential in biomedical
applications. Previously, we have synthesized novel Zn2+-passivated carbon dots (Zn-CDs) …