Improved reference genome of Aedes aegypti informs arbovirus vector control

BJ Matthews, O Dudchenko, SB Kingan, S Koren… - Nature, 2018 - nature.com
Female Aedes aegypti mosquitoes infect more than 400 million people each year with
dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress …

The vectors of Plasmodium knowlesi and other simian malarias Southeast Asia: challenges in malaria elimination

I Vythilingam, TH Chua, JWK Liew, BO Manin… - Advances in …, 2021 - Elsevier
Plasmodium knowlesi, a simian malaria parasite of great public health concern has been
reported from most countries in Southeast Asia and exported to various countries around the …

Microsporidia: a promising vector control tool for residual malaria transmission

T Bukhari, R Pevsner, JK Herren - Frontiers in Tropical Diseases, 2022 - frontiersin.org
Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) have resulted in a
major decrease in malaria transmission. However, it has become apparent that malaria can …

Visualizing population structure with variational autoencoders

CJ Battey, GC Coffing, AD Kern - G3, 2021 - academic.oup.com
Dimensionality reduction is a common tool for visualization and inference of population
structure from genotypes, but popular methods either return too many dimensions for easy …

Gene family evolution in the pea aphid based on chromosome-level genome assembly

Y Li, H Park, TE Smith, NA Moran - Molecular biology and …, 2019 - academic.oup.com
Genome structural variations, including duplications, deletions, insertions, and inversions,
are central in the evolution of eukaryotic genomes. However, structural variations present …

The relationship between insecticide resistance, mosquito age and malaria prevalence in Anopheles gambiae sl from Guinea

E Collins, NM Vaselli, M Sylla, AH Beavogui… - Scientific reports, 2019 - nature.com
Insecticide resistance across sub-Saharan Africa may impact the continued effectiveness of
malaria vector control. We investigated the association between carbamate and pyrethroid …

Coalescent Analysis of Phylogenomic Data Confidently Resolves the Species Relationships in the Anopheles gambiae Species Complex

Y Thawornwattana, D Dalquen… - Molecular biology and …, 2018 - academic.oup.com
Deep coalescence and introgression make it challenging to infer phylogenetic relationships
among closely related species that arose through radiative speciation events. Despite …

A chromosome-scale assembly of the major African malaria vector Anopheles funestus

J Ghurye, S Koren, ST Small, S Redmond… - …, 2019 - academic.oup.com
Background Anopheles funestus is one of the 3 most consequential and widespread vectors
of human malaria in tropical Africa. However, the lack of a high-quality reference genome …

LLIN Evaluation in Uganda Project (LLINEUP): a cross-sectional survey of species diversity and insecticide resistance in 48 districts of Uganda

A Lynd, S Gonahasa, SG Staedke, A Oruni… - Parasites & vectors, 2019 - Springer
Background Long-lasting insecticidal nets (LLINs) are the principal tool for malaria control in
Africa and are presently treated with a single class of insecticide; however, increasing levels …

Evolution of the Insecticide Target Rdl in African Anopheles Is Driven by Interspecific and Interkaryotypic Introgression

X Grau-Bové, S Tomlinson, AO O'Reilly… - Molecular Biology …, 2020 - academic.oup.com
The evolution of insecticide resistance mechanisms in natural populations of Anopheles
malaria vectors is a major public health concern across Africa. Using genome sequence …