Four decades after the first isolation and characterization of clonogenic bone marrow stromal cells or mesenchymal stem cells (MSC) in the laboratory of Dr. Alexander …
Background Hospital charges for lumbar spinal stenosis have increased significantly worldwide in recent times, with great variation in the costs and rates of different surgical …
Study design: Systematic review. Study rationale: Some have noted several safety issues associated with the use of bone morphogenetic proteins (BMPs), including cancer risk …
A Kadam, PW Millhouse, CK Kepler… - International Journal of …, 2016 - ijssurgery.com
Study Design A narrative review of literature. Objective This manuscript intends to provide a review of clinically relevant bone substitutes and bone expanders for spinal surgery in terms …
In an attempt to enhance the potential to achieve a solid arthrodesis and avoid the morbidity of harvesting autologous iliac crest bone (AICB) for a lumbar fusion, numerous alternatives …
K Singh, K Ahmadinia, DK Park, SV Nandyala… - Spine, 2014 - journals.lww.com
Study Design. Systematic review. Objective. A systematic review was performed to identify the types of complications and complication rates associated with the use of bone …
CP Hofstetter, AS Hofer, AD Levi - Journal of Neurosurgery: Spine, 2016 - thejns.org
OBJECT Bone morphogenetic protein (BMP) is frequently used for spinal arthrodesis procedures in an “off-label” fashion. Whereas complications related to BMP usage are well …
S Liu, Y Wang, Z Liang, M Zhou, C Chen - Spine, 2020 - journals.lww.com
Study Design. This is a systematic literature review and meta-analysis. Objective. We aimed to evaluate the efficacy and safety of recombinant human bone morphogenetic protein …
Background: Spinal fusion with the use of autograft is a commonly performed procedure. However, harvesting of bone from the iliac crest is associated with complications. Bone …