Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …

ATG5 is a part of the E3 ligase directing lipidation of ATG8 proteins, a process central to
membrane atg8ylation and canonical autophagy. Loss of Atg5 in myeloid cells causes early …

Immune cell membrane coated nanomedicine was developed to neutralize cytokines via
receptor-ligand interaction, which showed potential for the treatment of inflammatory bowel …

Cytolethal distending toxin (CDT) is produced by a range of Gram-negative pathogenic
bacteria such as Campylobacter jejuni. CDT represents an important virulence factor that is …

Professional phagocytes like neutrophils and macrophages tightly control what they
consume, how much they consume, and when they move after cargo uptake. We show that …

Pathogenic infection leads to excessive senescent cell accumulation and stagnation of
wound healing. To address these issues, we devise and develop a hydrogen selenide (H 2 …

As a classic noninvasive physiotherapy, photobiomodulation, also known as low-level laser
therapy, is widely used for the treatment of many diseases and has anti-inflammatory and …

Immune adjuvants have roles in immune activation for cancer therapy, and adjuvants
derived from microbes have been applied. In this study, we propose the use of …

Gaucher disease (GD) stands as one of the most prevalent lysosomal disorders, yet
neuronopathic GD (nGD) is an uncommon subset characterized by a wide array of clinical …