Towards microfluidic-based exosome isolation and detection for tumor therapy
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …
membrane structure of 30–150 nm in diameter. Their discovery and application have …
Extracellular vesicles as therapeutic resources in the clinical environment
J Sanz-Ros, C Mas-Bargues, N Romero-García… - International journal of …, 2023 - mdpi.com
The native role of extracellular vesicles (EVs) in mediating the transfer of biomolecules
between cells has raised the possibility to use them as therapeutic vehicles. The …
between cells has raised the possibility to use them as therapeutic vehicles. The …
[HTML][HTML] Isolation of exosomes by differential centrifugation: Theoretical analysis of a commonly used protocol
MA Livshits, E Khomyakova, EG Evtushenko… - Scientific reports, 2015 - nature.com
Abstract Exosomes, small (40–100 nm) extracellular membranous vesicles, attract
enormous research interest because they are carriers of disease markers and a prospective …
enormous research interest because they are carriers of disease markers and a prospective …
Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches
Clinical implementation of exosome based diagnostic and therapeutic applications is still
limited by the lack of standardized technologies that integrate efficient isolation of exosomes …
limited by the lack of standardized technologies that integrate efficient isolation of exosomes …
Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
Developing blood-based tests is appealing for non-invasive disease diagnosis, especially
when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes …
when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes …
Human endometrial exosomes contain hormone-specific cargo modulating trophoblast adhesive capacity: insights into endometrial-embryo interactions
DW Greening, HPT Nguyen, K Elgass… - Biology of …, 2016 - academic.oup.com
Embryo implantation into receptive endometrium requires synergistic endometrial-blastocyst
interactions within the uterine cavity and is essential for establishing pregnancy. We …
interactions within the uterine cavity and is essential for establishing pregnancy. We …
Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically …
Secretion and exchange of extracellular vesicles (EVs) by most cell types is emerging as a
fundamental biological process. Although much is known about EVs, there is still a lack of …
fundamental biological process. Although much is known about EVs, there is still a lack of …
Size separation of exosomes and microvesicles using flow field-flow fractionation/multiangle light scattering and lipidomic comparison
Extracellular vesicles (EVs) are cell-derived membrane-bound particles, including
exosomes and microvesicles that differ in cellular origin, content, and lipid composition. This …
exosomes and microvesicles that differ in cellular origin, content, and lipid composition. This …
[HTML][HTML] Isolation of syncytiotrophoblast microvesicles and exosomes and their characterisation by multicolour flow cytometry and fluorescence Nanoparticle Tracking …
RA Dragovic, GP Collett, P Hole, DJP Ferguson… - Methods, 2015 - Elsevier
The human placenta releases multiple types and sizes of syncytiotrophoblast (STB)
extracellular vesicles (EV) into the maternal circulation that exhibit diverse biological …
extracellular vesicles (EV) into the maternal circulation that exhibit diverse biological …
Enhancing the stabilization potential of lyophilization for extracellular vesicles
E Trenkenschuh, M Richter, E Heinrich… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EV) are an emerging technology as immune therapeutics and drug
delivery vehicles. However, EVs are usually stored at− 80° C which limits potential clinical …
delivery vehicles. However, EVs are usually stored at− 80° C which limits potential clinical …