Cellular membranes are constantly reshaped by vesicular fission and fusion as well as by
interactions with the dynamic cytoskeleton. Signaling activity at membranes depends on …

Mammalian and bacterial cells sense and exert mechanical forces through the process of
mechanotransduction, which interconverts biochemical and physical signals. This is …

The quantification of membrane-associated biomolecular interactions is crucial to our
understanding of various cellular processes. State-of-the-art single-molecule approaches …

The synaptic vesicle protein Synaptophysin (Syp) has long been known to form a complex
with the Vesicle associated soluble N-ethylmaleimide sensitive fusion protein attachment …

KRas is a major proto-oncogene product whose signaling activity depends on its level of
enrichment on the plasma membrane (PM). This PM localization relies on posttranslational …

AB5 bacterial toxins and polyomaviruses induce membrane curvature as a mechanism to
facilitate their entry into host cells. How membrane bending is accomplished is not yet fully …

Although the human immunodeficiency virus type 1 lipid envelope has been reported to be
enriched with host cell sphingomyelin and cholesterol, the molecular mechanism of the …

Membrane protein interactions with lipids are crucial for their native biological behavior, yet
traditional characterization methods are often carried out on purified protein in the absence …

Epithelial (E)-cadherin-mediated cell− cell junctions play important roles in the development
and maintenance of tissue structure in multicellular organisms. E-cadherin adhesion is thus …

Lipids and proteins are the main components of cell membranes. It is becoming increasingly
clear that lipids, in addition to providing an environment for proteins to work in, are in many …