[HTML][HTML] tRNA-derived small RNA: a novel regulatory small non-coding RNA

S Li, Z Xu, J Sheng - Genes, 2018 - mdpi.com
Deep analysis of next-generation sequencing data unveils numerous small non-coding
RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA …

[HTML][HTML] Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe‐host‐communication in vivo

M Bittel, P Reichert, I Sarfati, A Dressel… - Journal of …, 2021 - Wiley Online Library
The intestinal microbiota influences mammalian host physiology in health and disease
locally in the gut but also in organs devoid of direct contact with bacteria such as the liver …

[HTML][HTML] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids

OD Murillo, W Thistlethwaite, J Rozowsky… - Cell, 2019 - cell.com
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …

[HTML][HTML] Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation

S Srinivasan, A Yeri, PS Cheah, A Chung, K Danielson… - Cell, 2019 - cell.com
Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

[HTML][HTML] Large differences in small RNA composition between human biofluids

PM Godoy, NR Bhakta, AJ Barczak, H Cakmak… - Cell reports, 2018 - cell.com
Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular
communication and may be useful as disease biomarkers. We systematically compared …

[HTML][HTML] The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research

S Das, AB Abdel-Mageed, C Adamidi, PD Adelson… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

[HTML][HTML] exceRpt: a comprehensive analytic platform for extracellular RNA profiling

J Rozowsky, RR Kitchen, JJ Park, TR Galeev, J Diao… - Cell systems, 2019 - cell.com
Small RNA sequencing has been widely adopted to study the diversity of extracellular RNAs
(exRNAs) in biofluids; however, the analysis of exRNA samples can be challenging: they are …

Human plasma and serum extracellular small RNA reference profiles and their clinical utility

KEA Max, K Bertram, KM Akat… - Proceedings of the …, 2018 - National Acad Sciences
Circulating extracellular RNAs (exRNAs) have the potential to serve as biomarkers for a
wide range of medical conditions. However, limitations in existing exRNA isolation methods …

[HTML][HTML] Clinical and biological significance of circulating tumor cells, circulating tumor DNA, and exosomes as biomarkers in colorectal cancer

S Jia, R Zhang, Z Li, J Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) has been the fourth leading cause of cancer-related mortality
worldwide. Owing to clonal evolution and selection, CRC treatment needs multimodal …