Parkinson's disease is a common movement disorder seen in neurological practice, but the
diagnosis and management is challenging. The diagnosis is clinical and sometimes difficult …

Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

Introduction This registry evaluated the 24-month safety and efficacy of levodopa-carbidopa
intestinal gel (LCIG) treatment in advanced Parkinson's disease (PD) patients under routine …

Levodopa is the most effective medication for the treatment of the motor symptoms of
Parkinson's disease. However, over time, the clinical response to levodopa becomes …

As Parkinson's disease (PD) progresses, treatment needs to be adapted to maintain
symptom control. Once patients develop advanced PD, an optimised regimen of oral and …

Introduction Levodopa/carbidopa intestinal gel (LCIG; carbidopa/levodopa enteral
suspension) has been widely used and studied for the treatment of motor fluctuations in …

Levodopa‐induced motor complications remain an important source of disability for many
patients with Parkinson's disease. Substantial laboratory evidence indicates that motor …

A drug challenge test in Parkinson's disease, such as the levodopa challenge test (LCT), is
an easy and generally safe procedure, which has been used by clinicians for various …

Parkinson Disease (Japanese Version) Page 1 Annals of Internal Medicine® In the Clinic®
パーキンソン 病 パーキンソン病は進行性の運動および非運動障害を 引き起こすありふれた神経変性 …

Levodopa is the most effective antiparkinsonian agent, but chronic treatment is associated
with the development of motor complications in the majority of patients with PD. Recent …