Vinyl epoxides in organic synthesis

J He, J Ling, P Chiu - Chemical Reviews, 2014 - ACS Publications
Vinyl epoxides are molecules with a rich chemistry because of the strained oxirane, already
a reactive moiety on its own, in proximity with a carbon− carbon double bond. The chemistry …

In the arena of enantioselective synthesis, titanium complexes wear the laurel wreath

DJ Ramon, M Yus - Chemical reviews, 2006 - ACS Publications
Asymmetry is ubiquitous in every part of Nature1 and has a great impact in many fields, not
only in chemistry but also even in arts. In the pharmaceutical area, asymmetry plays an …

Bismuth nitrate-catalyzed multicomponent reaction for efficient and one-pot synthesis of densely functionalized piperidine scaffolds at room temperature

G Brahmachari, S Das - Tetrahedron Letters, 2012 - Elsevier
A simple, straightforward, and highly efficient diastereoselective multicomponent one-pot
synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives …

Synthesis of highly functionalized piperidines by one-pot multicomponent reaction using tetrabutylammonium tribromide (TBATB)

AT Khan, M Lal, MM Khan - Tetrahedron Letters, 2010 - Elsevier
Tetrabutylammonium tribromide (TBATB) has been found to be an efficient catalyst for the
one-pot synthesis of highly substituted piperidines through a combination of 1, 3-dicarbonyl …

Effects of substituents in the β-position of 1, 3-dicarbonyl compounds in bromodimethylsulfonium bromide-catalyzed multicomponent reactions: a facile access to …

AT Khan, T Parvin, LH Choudhury - The Journal of organic …, 2008 - ACS Publications
1, 3-Dicarbonyl compounds can be converted to Mannich-type products A or highly
functionalized piperidines B in the presence of a catalytic amount of …

Iodine catalyzed one-pot five-component reactions for direct synthesis of densely functionalized piperidines

AT Khan, MM Khan, KKR Bannuru - Tetrahedron, 2010 - Elsevier
A simple and convenient one-pot multicomponent reaction (MCR) has been developed for
the synthesis of highly functionalized piperidines catalyzed by molecular iodine. This …

Natural and synthetic iminosugars as carbohydrate processing enzyme inhibitors for cancer therapy

TM Wrodnigg, AJ Steiner… - Anti-Cancer Agents in …, 2008 - ingentaconnect.com
Iminosugars, featuring a basic nitrogen at the hetero atom position in carbohydrate rings,
gain increasing interest in the search for novel approaches towards cancer drug …

Achmatowicz reaction and its application in the syntheses of bioactive molecules

AK Ghosh, M Brindisi - RSC advances, 2016 - pubs.rsc.org
Substituted pyranones and tetrahydropyrans are structural subunits of many bioactive
natural products. Considerable effort is devoted toward the chemical synthesis of these …

Recent Advances in the Synthesis and Ring‐Opening Transformations of 2‐Oxazolidinones

F Sun, EV Van der Eycken… - Advanced Synthesis & …, 2021 - Wiley Online Library
Oxazolidinone represents a class of most important five‐membered cyclic carbamates. They
are of great significance for modern organic synthesis and are widespread as …

Targeted drugs by olefin metathesis: piperidine-based iminosugars

I Dragutan, V Dragutan, A Demonceau - RSC advances, 2012 - pubs.rsc.org
Examining advances in the class of natural and non-natural piperidine azasugars, important
therapeutic agents and potent glycosidase inhibitors, this review looks at syntheses applying …