Neurocognitive function after cardiac surgery: from phenotypes to mechanisms

M Berger, N Terrando, SK Smith… - …, 2018 - pmc.ncbi.nlm.nih.gov
For half a century, we have known that some patients experience neurocognitive dysfunction
after cardiac surgery, yet defining its incidence, course, and causes remains challenging …

[HTML][HTML] Risk of stroke after transcatheter aortic valve implantation (TAVI): a meta-analysis of 10,037 published patients

H Eggebrecht, A Schmermund… - Database of Abstracts …, 2012 - ncbi.nlm.nih.gov
This review found that transcatheter aortic valve implantation was associated with a stroke
rate of 3.3% and a mortality rate of 8.1% in the first 30 days following surgery. While this …

Protection against cerebral embolism during transcatheter aortic valve replacement

SR Kapadia, S Kodali, R Makkar, R Mehran… - Journal of the American …, 2017 - jacc.org
Background: Neurological complications after transcatheter aortic valve replacement (TAVR)
may be reduced with transcatheter cerebral embolic protection (TCEP). Objectives: This …

Effect of a cerebral protection device on brain lesions following transcatheter aortic valve implantation in patients with severe aortic stenosis: the CLEAN-TAVI …

S Haussig, N Mangner, MG Dwyer, L Lehmkuhl… - Jama, 2016 - jamanetwork.com
Importance Stroke remains a major predictor of mortality after transcatheter aortic valve
implantation (TAVI). Cerebral protection devices might reduce brain injury as determined by …

A prospective randomized evaluation of the TriGuard™ HDH embolic DEFLECTion device during transcatheter aortic valve implantation: results from the DEFLECT III …

AJ Lansky, J Schofer, D Tchetche, P Stella… - European heart …, 2015 - academic.oup.com
Aims To evaluate the safety, efficacy, and performance of the TriGuard™ HDH Embolic
Deflection Device (TriGuard) compared with no cerebral protection in patients undergoing …

Cerebral embolic protection during transcatheter aortic valve replacement significantly reduces death and stroke compared with unprotected procedures

J Seeger, B Gonska, M Otto, W Rottbauer… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to evaluate the impact of cerebral embolic protection
on stroke-free survival in patients undergoing transcatheter aortic valve replacement …

Randomized evaluation of TriGuard 3 cerebral embolic protection after transcatheter aortic valve replacement: REFLECT II

TM Nazif, J Moses, R Sharma, A Dhoble, J Rovin… - Cardiovascular …, 2021 - jacc.org
Abstract Objectives The REFLECT II (Randomized Evaluation of TriGuard 3 Cerebral
Embolic Protection After Transcatheter Aortic Valve Implantation) trial was designed to …

A randomized evaluation of the TriGuard™ HDH cerebral embolic protection device to Reduce the Impact of Cerebral Embolic LEsions after TransCatheter Aortic …

AJ Lansky, R Makkar, T Nazif, S Messé… - European heart …, 2021 - academic.oup.com
Abstract Aims The REFLECT I trial investigated the safety and effectiveness of the
TriGuard™ HDH (TG) cerebral embolic deflection device in patients undergoing …

Antithrombotic treatment in transcatheter aortic valve implantation: insights for cerebrovascular and bleeding events

J Rodés-Cabau, HL Dauerman, MG Cohen… - Journal of the American …, 2013 - jacc.org
Transcatheter aortic valve implantation (TAVI) has emerged as a therapeutic alternative for
patients with symptomatic aortic stenosis at high or prohibitive surgical risk. However …

Rate of peri-procedural stroke observed with cerebral embolic protection during transcatheter aortic valve replacement: a patient-level propensity-matched analysis

J Seeger, SR Kapadia, S Kodali, A Linke… - European Heart …, 2019 - academic.oup.com
Aims The role of cerebral embolic protection (CEP) in transcatheter aortic valve replacement
(TAVR) remains controversial. Randomized trials have not been powered to demonstrate a …