Chronic pain in the elderly: mechanisms and perspectives

APA Dagnino, MM Campos - Frontiers in Human Neuroscience, 2022 - frontiersin.org
Chronic pain affects a large part of the population causing functional disability, being often
associated with coexisting psychological disorders, such as depression and anxiety …

Cholinergic modulation of glial function during aging and chronic neuroinflammation

R Gamage, I Wagnon, I Rossetti, R Childs… - Frontiers in Cellular …, 2020 - frontiersin.org
Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective

MM Mielke, NT Aggarwal, C Vila‐Castelar… - Alzheimer's & …, 2022 - Wiley Online Library
Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD)
differ by world region, suggesting that there are potentially modifiable risk factors for …

The link between chronic pain and Alzheimer's disease

S Cao, DW Fisher, T Yu, H Dong - Journal of neuroinflammation, 2019 - Springer
Chronic pain often occurs in the elderly, particularly in the patients with neurodegenerative
disorders such as Alzheimer's disease (AD). Although studies indicate that chronic pain …

Pattern of treatment of behavioural and psychological symptoms of dementia and pain: Evidence on pharmacoutilization from a large real-world sample and from a …

D Scuteri, M Vulnera, B Piro, RB Bossio… - European journal of …, 2021 - Springer
Purpose Data concerning the number of diagnoses and of the drugs prescribed to patients
affected by dementia are still scarce. Here we test whether or not (1) prescription of …

Association of persistent musculoskeletal pain with dementia risk score in adults aged 45 years or older: the China health and retirement longitudinal study

YN Zheng, H Liu, PJ Chen, XQ Wang - Brain, Behavior, and Immunity, 2024 - Elsevier
Background Recent studies have confirmed an association between pain and dementia.
Whether musculoskeletal pain in the spine, upper limbs, and lower limbs is associated with …

Association between chronic pain and risk of incident dementia: findings from a prospective cohort

J Tian, G Jones, X Lin, Y Zhou, A King, J Vickers, F Pan - BMC medicine, 2023 - Springer
Background Chronic musculoskeletal pain has been linked to dementia; however, chronic
pain typically occurs in multiple sites; therefore, this study was to investigate whether greater …

Association between chronic pain and long-term cognitive decline in a population-based cohort of elderly participants

I Rouch, A Edjolo, B Laurent, E Pongan, JF Dartigues… - Pain, 2021 - journals.lww.com
Chronic pain (CP) was associated with impaired cognitive performance in several cross-
sectional studies conducted in older adults; however, fewer longitudinal studies assessed …

Pain, opioid analgesics, and cognition: A conceptual framework in older adults

NS Warner, MM Mielke, BP Verdoorn… - Pain …, 2023 - academic.oup.com
Chronic pain is highly prevalent in older adults and is associated with poor functional
outcomes. Furthermore, opioid analgesics are commonly utilized for the treatment of pain in …

An exploratory analysis of contributors to cognitive functioning among sexual and gender minority individuals who had COVID-19

OY Franco-Rocha, KA Lewis, SR Kesler… - Journal of …, 2025 - Taylor & Francis
Sexual and gender minority (SGM) individuals face mental health disparities. However,
research analyzing SGM people's mental health after a COVID-19 diagnosis is scarce. In …