Promising targeted treatments and immunotherapy strategies in oncology and
advancements in our understanding of molecular pathways that underpin cancer …

Members of the GroEL/HSP60 protein family have been studied for many years because of
their critical roles as ATP-dependent molecular chaperones, so it might come as a surprise …

Folate, an essential nutrient found naturally in foods in a reduced form, is present in dietary
supplements and fortified foods in an oxidized synthetic form (folic acid). There is …

Traditional cancer chemotherapy easily produces serious toxic and side effects due to the
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …

Triple negative breast cancer (TNBC) is a subtype of breast cancer characterized by
absence of estrogen (ER) receptor, progesterone (PR) receptor, and human epidermal …

Hepatic fibrosis is the primary determinant of mortality in patients with metabolic dysfunction–
associated steatohepatitis (MASH). Transforming growth factor–β (TGFβ), a master …

Novel conjugated carbon dots (CDs) were synthesized as two-photon active
photosensitisers to unleash lethal reactive oxygen species (ROS) for nucleus-targeting …

Folate is a B vitamin necessary for basic biological functions, including rapid cell turnover
occurring in cancer cell proliferation. Though the role of folate as a causative versus …

Gastric cancer is a malignancy that has a high mortality rate. Although progress has been
made in the treatment of gastric cancer, many patients experience cancer recurrence and …

Folates are B vitamins that function in one-carbon metabolism. Folate receptors are one of
three major types of folate transporters. The folate receptors FOLR1 and FOLR2 are …