Liver transplantation is the ultimate treatment for severe hepatic failure to date. However, the
limited supply of donor organs has severely hampered this treatment. So far, great potentials …

Repair of injured lungs represents a longstanding therapeutic challenge. We show that
human and mouse embryonic lung tissue from the canalicular stage of development (20–22 …

Bonavita AG, Quaresma K, Cotta‐de‐Almeida V, Alves Pinto M, Magalhães Saraiva R,
Anastácio Alves L. Hepatocyte xenotransplantation for treating liver disease …

Many diseases that manifest throughout the lifetime are influenced by factors affecting fetal
development. Fetal exposure to xenobiotics, in particular, may influence the development of …

OBJECTIVE Defining an optimal costimulatory blockade–based immune suppression
protocol enabling engraftment and functional development of E42 pig embryonic pancreatic …

A simple culture system to achieve the differentiation of embryonic stem (ES) cells toward
hepatocytes with high efficiency is crucial in providing a cell source for the medical …

Objectives: Utility of hepatic stem cells could provide a novel solution to the severe shortage
of human donor livers, for treatment of liver‐related diseases, due to their ability to proliferate …

How to improve the wound healing quality of severe burn patients is still a challenge due to
lack of skin appendages and rete ridges, no matter how much progress has been made in …

A critical shortage of donor organs for treating end-stage organ failure highlights the urgent
need for generating organs from human induced pluripotent stem cells (iPSCs). Despite …

Background. Xenogeneic embryonic pancreatic tissue can provide an attractive alternative
for organ replacement therapy. However, immunological rejection represents a major …