Simple Summary The success of HPV as an infectious agent lies not within its ability to
cause disease, but rather in the adeptness of the virus to establish long-term persistent …

Decades of research on the human papillomavirus oncogenes, E6 and E7, have given us
huge amounts of data on their expression, functions and structures. We know much about …

Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses
infecting human epithelial cells, are associated with various benign and malignant lesions of …

Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor (BLT), is a rare
disease of the anogenital region. BLT is considered a locally aggressive tumor of benign …

Human papillomaviruses (HPV) cause persistent infections by modulating epithelial
homeostasis in cells of the infected basal layer. Using FUCCI and cell-cell competition …

Human Papillomaviruses have co-evolved with their human host, with each of the over 200
known HPV types infecting distinct epithelial niches to cause diverse disease pathologies …

Human papillomaviruses establish a reservoir of infection in the epithelial basal layer. To do
this they limit their gene expression to avoid immune detection and modulate epithelial …

Papillomaviruses exclusively infect stratified epithelial tissues and cause chronic infections.
To achieve this, infected cells must remain in the epithelial basal layer alongside their …

Cervical, anogenital, and some head and neck cancers (HNC) are etiologically associated
with high-risk human papillomavirus (HR-HPV) infection, even though additional cofactors …

Papillomaviruses cause persistent, and usually self-limiting, infections in the mucosal and
cutaneous surfaces of the host epithelium. However, in some cases, infection with an …