The disaccharide trehalose plays a crucial role in multiple facets of the stress biology of
yeasts and fungi. Here, we evaluate the properties, cellular and ecophysiological roles …

In large scale fermentors the cultivated cells are exposed to dynamic changes in the nutrient
concentrations due to imperfect mixing. Based on the characterization of these nutrient …

The influence of extracellular variations on the cellular metabolism and thereby the process
performance at large-scale can be evaluated using the so-called scale-down simulators …

Bioreactor scale-up from the laboratory scale to the industrial scale has always been a
pivotal step in bioprocess development. However, the transition of a bioeconomy from …

In the food sector, fermentation processes have been the object of great interest in regard to
enhancing the yield, the quality, and the safety of the final product. Microbial fermentation …

As the youngest of the quartet of systems biology tools alongside genomics, transcriptomics,
and proteomics, metabolomics provides an immediate and dynamic recording of cells in …

While traveling through different zones in large‐scale bioreactors, microbes are most likely
subjected to fluctuating dissolved oxygen (DO) conditions at the timescales of global …

The benefits extended to human health by fermented foods are expressed either directly
through the interactions of ingested live microorganisms with the host (probiotic effect) or …