Vascular anomalies include various diseases, which are classified into two types according
to the International Society for the Study of Vascular Anomalies (ISSVA) classification …

Stroke is an important cause of neurological morbidity in children; most survivors have
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …

Cerebrovascular diseases are a leading cause of death and neurologic disability. Further
understanding of disease mechanisms and therapeutic strategies requires a deeper …

KRAS gain-of-function mutations are frequently observed in sporadic arteriovenous
malformations. The mechanisms underlying the progression of such KRAS-driven …

Cavernous malformations affecting the CNS occur in∼ 0.16–0.4% of the general population.
The majority (85%) of cavernous malformations are in a sporadic form, but the genetic …

Background The purpose of this review is to summarize the data available for the role of
angiography and embolization in the comprehensive multidisciplinary management of brain …

Objective Brain arteriovenous malformations (bAVMs) are a leading cause of hemorrhagic
stroke and neurological deficits in children and young adults, however, no pharmacological …

Brain arteriovenous malformations (AVMs) are a disorder wherein abnormal, enlarged blood
vessels connect arteries directly to veins, without an intervening capillary bed. AVMs are one …

Cerebral cavernous malformations (CCMs) and spinal cord cavernous malformations
(SCCMs) are common vascular abnormalities of the CNS that can lead to seizure …

Hereditary haemorrhagic telangiectasia (HHT) is characterised by arteriovenous
malformations (AVMs). These vascular abnormalities form when arteries and veins directly …