Conventional vaccine strategies have been highly efficacious for several decades in reducing mortality and morbidity due to infectious diseases. The bane of conventional …
DJ Barker, G Maccari, X Georgiou… - Nucleic acids …, 2023 - academic.oup.com
It is 24 years since the IPD-IMGT/HLA Database, http://www. ebi. ac. uk/ipd/imgt/hla/, was first released, providing the HLA community with a searchable repository of highly curated …
J Robinson, DJ Barker, X Georgiou… - Nucleic acids …, 2020 - academic.oup.com
Abstract The IPD-IMGT/HLA Database, http://www. ebi. ac. uk/ipd/imgt/hla/, currently contains over 25 000 allele sequence for 45 genes, which are located within the Major …
Abstract The Immuno Polymorphism Database (IPD) was developed to provide a centralized system for the study of polymorphism in genes of the immune system. Through the IPD …
SGE Marsh, ED Albert, WF Bodmer, RE Bontrop… - Tissue …, 2010 - ncbi.nlm.nih.gov
The WHO Nomenclature Committee for Factors of the HLA System met following the 14th International HLA and Immunogenetics Workshop in Melbourne, Australia in December …
J Trowsdale, JC Knight - Annual review of genomics and human …, 2013 - annualreviews.org
Over several decades, various forms of genomic analysis of the human major histocompatibility complex (MHC) have been extremely successful in picking up many …
The genetic association of the major histocompatibility complex (MHC) to rheumatoid arthritis risk has commonly been attributed to alleles in HLA-DRB1. However, debate …
X Jia, B Han, S Onengut-Gumuscu, WM Chen… - PloS one, 2013 - journals.plos.org
DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. The complex genetic structure of the major …
International HIV Controllers Study - Science, 2010 - science.org
Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility complex (MHC); however, the basis for these associations …