The eye is regarded as an immune privileged site. Since the presence of a vasculature
would impair vision, the vasculature of the eye is located outside of the central light path. As …

Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …

Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …

Therapeutic interventions that counter emerging targets in diabetes eye diseases are
lacking. We hypothesize that a combination therapy targeting inflammation and …

Functional hyperemia, or the matching of blood flow with activity, directs oxygen and
nutrients to regionally firing neurons. The mechanisms responsible for this spatial accuracy …

Purpose Photoreceptor degeneration occurs in various retinal diseases including age-
related macular degeneration (AMD), Retinitis pigmentosa (RP), and diabetic retinopathy …

Retinitis pigmentosa (RP) is an important cause of irreversible blindness worldwide and
lacks effective treatment strategies. Although mutations are the primary cause of RP …

Besides cystoid macular edema due to a blood-retinal barrier breakdown, another type of
macular cystoid spaces referred to as non-vasogenic cystoid maculopathies (NVCM) may be …

The retina, the part of the eye, translates the light signal into an electric current that can be
sent to the brain as visual information. To achieve this, the retina requires fine-tuned …