The ATP synthase: the understood, the uncertain and the unknown

JE Walker - Biochemical Society Transactions, 2013 - portlandpress.com
The ATP synthases are multiprotein complexes found in the energy-transducing membranes
of bacteria, chloroplasts and mitochondria. They employ a transmembrane protonmotive …

[HTML][HTML] The molecular mechanism of ATP synthesis by F1F0-ATP synthase

AE Senior, S Nadanaciva, J Weber - Biochimica et Biophysica Acta (BBA) …, 2002 - Elsevier
ATP synthesis by oxidative phosphorylation and photophosphorylation, catalyzed by F1F0-
ATP synthase, is the fundamental means of cell energy production. Earlier mutagenesis …

Structure of the dimeric ATP synthase from bovine mitochondria

TE Spikes, MG Montgomery… - Proceedings of the …, 2020 - National Acad Sciences
The structure of the dimeric ATP synthase from bovine mitochondria determined in three
rotational states by electron cryo-microscopy provides evidence that the proton uptake from …

Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols

JR Gledhill, MG Montgomery… - Proceedings of the …, 2007 - National Acad Sciences
The structures of F1-ATPase from bovine heart mitochondria inhibited with the dietary
phytopolyphenol, resveratrol, and with the related polyphenols quercetin and piceatannol …

[HTML][HTML] Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen

D Gai, R Zhao, D Li, CV Finkielstein, XS Chen - Cell, 2004 - cell.com
The large tumor antigen (LTag) of simian virus 40, an AAA+ protein, is a hexameric helicase
essential for viral DNA replication in eukaryotic cells. LTag functions as an efficient …

[HTML][HTML] ATP synthesis driven by proton transport in F1F0-ATP synthase

J Weber, AE Senior - FEBS letters, 2003 - Elsevier
Topical questions in ATP synthase research are:(1) how do protons cause subunit rotation
and how does rotation generate ATP synthesis from ADP+ Pi?(2) How does hydrolysis of …

Structure of the ATP synthase catalytic complex (F1) from Escherichia coli in an autoinhibited conformation

G Cingolani, TM Duncan - Nature structural & molecular biology, 2011 - nature.com
ATP synthase is a membrane-bound rotary motor enzyme that is critical for cellular energy
metabolism in all kingdoms of life. Despite conservation of its basic structure and function …

A comparative study of motor-protein motions by using a simple elastic-network model

W Zheng, S Doniach - … of the National Academy of Sciences, 2003 - National Acad Sciences
In this work, we report on a study of the structure-function relationships for three families of
motor proteins, including kinesins, myosins, and F1-ATPases, by using a version of the …

The structure of bovine F1‐ATPase inhibited by ADP and beryllium fluoride

R Kagawa, MG Montgomery, K Braig… - The EMBO …, 2004 - embopress.org
The structure of bovine F1‐ATPase inhibited with ADP and beryllium fluoride at 2.0 Å
resolution contains two ADP. BeF3− complexes mimicking ATP, bound in the catalytic sites …

[图书][B] What sustains life?: consilient mechanisms for protein-based machines and materials

DW Urry - 2007 - books.google.com
In the sixth century BC, Thales of Miletus, father of the Ionian Enhghtenment, setting aside
the mythic views of Homer and Hesiod asked," What is the world made of?" and thereby …