[HTML][HTML] Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry

EO Mensah, ON Kanwugu, PK Panda, P Adadi - Food Hydrocolloids, 2023 - Elsevier
Over the years, seaweeds have been highlighted as valuable natural sources of bioactive
polysaccharides. Fucoidan, a sulphated polysaccharide mainly from brown seaweeds …

A critical review on pharmacological properties of sulfated polysaccharides from marine macroalgae

B Jegadeshwari, R Rajaram - Carbohydrate Polymers, 2024 - Elsevier
The marine ecosystem contains an assorted range of organisms, among which macroalgae
stands out marine resources as an invaluable reservoir of structurally diverse bioactive …

Atheroprotective effect of fucoidan in THP-1 macrophages by potential upregulation of ABCA1

Z Mirza, DA Al-Saedi, S Saddeek, S Almowallad… - Biomedicines, 2023 - mdpi.com
Targeting foam cells reduces the risk and pathophysiology of atherosclerosis, of which they
are one of its early hallmarks. The precise mechanism of action of fucoidan, a potential anti …

Oligosaccharides as potential therapeutics against atherosclerosis

SA Dabravolski, VN Sukhorukov, AA Melnichenko… - Molecules, 2023 - mdpi.com
Atherosclerosis is the major cause of cardiovascular-disease-related death worldwide,
resulting from the subendothelial accumulation of lipoprotein-derived cholesterol, ultimately …

Therapeutic potential of fucoidan in central nervous system disorders: A systematic review

J Yang, H Zhao, S Qu - International Journal of Biological Macromolecules, 2024 - Elsevier
Central nervous system (CNS) disorders have a complicated pathogenesis, and to date, no
single mechanism can fully explain them. Most drugs used for CNS disorders primarily aim …

Fucoidan's molecular targets: A comprehensive review of its unique and multiple targets accounting for promising bioactivities supported by in silico studies

A Zayed, DA Al-Saedi, EO Mensah, ON Kanwugu… - Marine Drugs, 2023 - mdpi.com
Fucoidan is a class of multifunctional polysaccharides derived from marine organisms. Its
unique and diversified physicochemical and chemical properties have qualified them for …

Preclinical insights into fucoidan as a nutraceutical compound against perfluorooctanoic acid-associated obesity via targeting endoplasmic reticulum stress

J Liu, C Guo, Y Wang, M Su, W Huang, KP Lai - Frontiers in Nutrition, 2022 - frontiersin.org
Obesity is a growing global health problem; it has been forecasted that over half of the
global population will be obese by 2030. Obesity is complicated with many diseases, such …

In silico molecular docking, molecular dynamics, ADMET analysis of fucoidan against receptor frizzled-8 and coreceptor LRP6 in Wnt/β-Catenin pathway and in vitro …

RA Laeliocattleya, Y Yunianta, Y Risjani… - Journal of …, 2024 - Taylor & Francis
This study aimed to investigate the effect of fucoidan on the Wnt/β-Catenin pathway using
both in-silico molecular docking, molecular dynamics, ADMET analysis (in frizzled-8 …

Dual-Targeting EGCG/NO-Supplying protein assembled nanoparticles with Multi-Synergistic effects against atherosclerosis

C Lin, TM Cheng, YC Liu, FY Hsu, CM Shih… - Chemical Engineering …, 2024 - Elsevier
Limited therapeutic options are available to effectively preventing atherosclerosis.
Inflammatory endothelial cells, foamy macrophages, and high protease levels contribute to …

Dermo-cosmetic potential of fucoidans

A Naghipour, P Zare, MA Langarizadeh… - Journal of Applied …, 2025 - Springer
Nowadays skin care products and the use of topical agents are widespread due to changes
in lifestyles. Natural skin care products have captured consumer attention because of their …