Supplementing with creatine is very popular amongst athletes and exercising individuals for
improving muscle mass, performance and recovery. Accumulating evidence also suggests …

While the vast majority of research involving creatine supplementation has focused on
skeletal muscle, there is a small body of accumulating research that has focused on creatine …

Nutrition usually makes a small but potentially valuable contribution to successful
performance in elite athletes, and dietary supplements can make a minor contribution to this …

Some dietary supplements are recommended to athletes based on data that supports
improved exercise performance. Other dietary supplements are not ergogenic per se, but …

There is a robust and compelling body of evidence supporting the ergogenic and
therapeutic role of creatine supplementation in muscle. Beyond these well-described effects …

The pleiotropic effects of creatine (Cr) are based mostly on the functions of the enzyme
creatine kinase (CK) and its high-energy product phosphocreatine (PCr). Multidisciplinary …

There is emerging interest regarding the potential beneficial effects of creatine
supplementation on indices of brain health and function. Creatine supplementation can …

Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell,
creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption …

The ergogenic and therapeutic effects of increasing muscle creatine by supplementation are
well-recognized. It appears that similar benefits to brain function and cognitive processing …

Single-voxel proton magnetic resonance imaging (1H-MRS) and proton MR spectroscopic
imaging (1H-MRSI) were used to compare brain metabolite levels in semi-acute mild …