The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Activated hepatic stellate cells (HSCs) and myofibroblasts are the main producers of
extracellular matrix (ECM) proteins that form the fibrotic tissue that leads to hepatic fibrosis …

Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate
inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for …

Skin tissue wound healing proceeds through four major stages, including hematoma
formation, inflammation, and neo-tissue formation, and culminates with tissue remodeling …

Wound healing is a multistep process with four overlapping but distinct stages: hemostasis,
inflammation, proliferation, and remodeling. An alteration at any stage may lead to the …

The chronic nature and associated complications of nonhealing wounds have led to the
emergence of nanotechnology-based therapies that aim at facilitating the healing process …

Silicon-based materials and their oxides are widely used in drug delivery, dietary
supplements, implants and dental fillers. Silica nanoparticles (SiNPs) interact with …

Historically, there has been a scarcity of evidence-based topical therapy to hasten the
healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged …

A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …