The human genetic epidemiology of COVID-19

MEK Niemi, MJ Daly, A Ganna - Nature Reviews Genetics, 2022 - nature.com
Human genetics can inform the biology and epidemiology of coronavirus disease 2019
(COVID-19) by pinpointing causal mechanisms that explain why some individuals become …

The disease severity and clinical outcomes of the SARS-CoV-2 variants of concern

L Lin, Y Liu, X Tang, D He - Frontiers in public health, 2021 - frontiersin.org
With the continuation of the pandemic, many severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of …

Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B. 1.1. 529) and delta (B. 1.617. 2) variants in England: a cohort …

T Nyberg, NM Ferguson, SG Nash, HH Webster… - The lancet, 2022 - thelancet.com
Background The omicron variant (B. 1.1. 529) of SARS-CoV-2 has demonstrated partial
vaccine escape and high transmissibility, with early studies indicating lower severity of …

Risk of hospitalisation associated with infection with SARS-CoV-2 omicron variant versus delta variant in Denmark: an observational cohort study

P Bager, J Wohlfahrt, S Bhatt, M Stegger… - The Lancet Infectious …, 2022 - thelancet.com
Background Estimates of the severity of the SARS-CoV-2 omicron variant (B. 1.1. 529) are
crucial to assess the public health impact associated with its rapid global dissemination. We …

[PDF][PDF] Living guidance for clinical management of COVID-19: living guidance, 23 November 2021

World Health Organization - 2021 - apps.who.int
This guideline is based on the above strategic priorities, and is intended for clinicians
involved in the care of patients with suspected or confirmed COVID-19. It is not meant to …

Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada

DN Fisman, AR Tuite - Cmaj, 2021 - Can Med Assoc
Background: Between February and June 2021, the initial wild-type strains of SARS-CoV-2
were supplanted in Ontario, Canada, by new variants of concern (VOCs), first those with the …

Severity of Omicron (B. 1.1. 529) and Delta (B. 1.617. 2) SARS-CoV-2 infection among hospitalised adults: a prospective cohort study in Bristol, United Kingdom

C Hyams, R Challen, R Marlow, J Nguyen… - The Lancet Regional …, 2023 - thelancet.com
Background There is an urgent public health need to evaluate disease severity in adults
hospitalised with Delta and Omicron SARS-CoV-2 variant infections. However, limited data …

Risk of reinfection, vaccine protection, and severity of infection with the BA. 5 omicron subvariant: a nation-wide population-based study in Denmark

CH Hansen, NU Friis, P Bager, M Stegger… - The Lancet infectious …, 2023 - thelancet.com
Background Estimates of immunity and severity for the SARS-CoV-2 omicron subvariant BA.
5 are important to assess the public health impact associated with its rapid global spread …

First and second COVID-19 waves in Brazil: A cross-sectional study of patients' characteristics related to hospitalization and in-hospital mortality

FA Zeiser, B Donida, CA da Costa… - The Lancet Regional …, 2022 - thelancet.com
Summary Background Background The second wave of the COVID-19 pandemic was more
aggressive in Brazil compared to other countries around the globe. Considering the …

The global epidemic of SARS‐CoV‐2 variants and their mutational immune escape

D Tian, YH Sun, JM Zhou, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
During the COVID‐19 pandemic, genetic variants of SARS‐CoV‐2 have been emerging and
spreading around the world. Several SARS‐CoV‐2 endemic variants were found in United …