Spermiogenesis is a long process whereby haploid spermatids derived from the meiotic
divisions of spermatocytes undergo metamorphosis into spermatozoa. It is subdivided into …

Aberrant sperm flagella impair sperm motility and cause male infertility, yet the genes which
have been identified in multiple morphological abnormalities of the flagella (MMAF) can only …

Gene-expression analysis studies from Schultz et al. estimate that more than 2,300 genes in
the mouse genome are expressed predominantly in the male germ line. As of their 2003 …

Sperm malformation is one of the main reasons for male infertility, but the precise
mechanisms of this process remain undiscovered. The major process of spermiogenesis is …

KIF3A motor protein is responsible for intraflagellar transport, which is required for protein
delivery during axoneme formation in ciliated cells. The function of KIF3A during …

Background The etiology of varicocele, a common cause of male factor infertility, remains
unclear. Proteomic changes responsible for the underlying pathology of unilateral varicocele …

Asthenozoospermia is one of the main factors leading to male infertility, but the genetic
mechanisms have not been fully elucidated. Variants in the androglobin (ADGB) gene were …

During spermiogenesis, haploid spermatids undergo dramatic morphological changes to
form slender sperm flagella and cap-like acrosomes, which are required for successful …

Objective: To define the cross-reactivity potential and the consequent autoimmunity intrinsic
to viral versus human peptide sharing. Methods: Using human papillomavirus (HPV) …

During spermiogenesis, the manchette is an important structure for sperm head and tail
formation. However, the mechanisms responsible for this process are poorly understood. In …