There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Bioorthogonal chemistry is a powerful tool to site-specifically activate drugs in living systems.
Bioorthogonal reactions between a pair of biologically reactive groups can rapidly and …

The interface of bio–nano science and cancer medicine is an area experiencing much
progress but also beset with controversy. Core concepts of the field eg, the enhanced …

Abstract The 2022 Nobel Prize in Chemistry was awarded to Professors K. Barry Sharpless,
Morten Meldal and Carolyn Bertozzi for their pioneering roles in the advent of click …

Bioorthogonal chemistry reactions occur in physiological conditions without interfering with
normal physiological processes. Through metabolic engineering, bioorthogonal groups can …

Pretargeted nuclear imaging and radiotherapy have recently attracted increasing attention
for diagnosis and treatment of cancer with nanomedicines. This is because it conceptually …

Biotin/(strept) avidin self-assembly is a powerful platform for nanoscale fabrication and
capture with many different applications in science, medicine, and nanotechnology …

Pretargeted imaging has emerged as a promising approach to advance nuclear imaging of
malignant tumors. Herein, we combine the enzyme‐mediated fluorogenic reaction and in …

The pretargeting strategy has recently emerged in order to overcome the limitations of direct
targeting, mainly in the field of radioimmunotherapy (RIT). This strategy is directly dependent …