Inflammatory bowel diseases (IBDs) consist of a group of chronic inflammatory disorders
with a complex etiology, which represent a clinical challenge due to their often therapy …

Angiogenesis is an important component of pathogenesis of inflammatory bowel disease
(IBD). Chronic inflammation and angiogenesis are two closely related processes. Chronic …

The aim of this study was to determine whether there are differences in absolute blood flow
between patients with Crohn's disease with inflammation or fibrosis using contrast …

Cardiovascular diseases (CVD) are the leading cause of mortality worldwide despite an
aggressive reduction of traditional cardiovascular risk factors. Underlying inflammatory …

Chronic ulcerative colitis (CUC) is characterized by increased intestinal epithelial cell (IEC)
apoptosis associated with elevated tumor necrosis factor (TNF), inducible nitric oxide …

The intestinal tract is a complex ecosystem where numerous cell types of epithelial, immune,
neuronal, and endothelial origin coexist in an intertwined, highly organized manner. The …

Ulcerative colitis is a dynamic, chronic inflammatory condition associated with an increased
colon cancer risk. Inflammatory cell apoptosis is a key mechanism regulating ulcerative …

Background Angiogenesis and vascular dysfunction play important roles in the occurrence
and development of Crohn's disease (CD), but relevant mechanistic research is lacking. This …

Background CDK8 is associated with the transcriptional Mediator complex and has been
shown to regulate several transcription factors implicated in cancer. As a pancreatic cancer …

Background The pathogenesis of Crohn's disease (CD) is unknown; however, angiogenesis
is known to play an important role in the disease. The present research suggests that …