[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications
CX Liu, LL Chen - Cell, 2022 - cell.com
Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …
Recent technological advances have in part overcome problems with their circular …
Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
The emerging roles of circRNAs in cancer and oncology
LS Kristensen, T Jakobsen, H Hager… - Nature reviews Clinical …, 2022 - nature.com
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …
non-coding RNA molecules, many of which have key roles in cancer development and …
Specific expression and functions of circular RNAs
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …
their covalently closed circular structure, have become a new research paradigm in RNA …
Biogenesis and regulatory roles of circular RNAs
Covalently closed, single-stranded circular RNAs can be produced from viral RNA genomes
as well as from the processing of cellular housekeeping noncoding RNAs and precursor …
as well as from the processing of cellular housekeeping noncoding RNAs and precursor …
Circular RNA: metabolism, functions and interactions with proteins
WY Zhou, ZR Cai, J Liu, DS Wang, HQ Ju, RH Xu - Molecular cancer, 2020 - Springer
Abstract Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules
that are ubiquitous across species ranging from viruses to mammals. Important advances …
that are ubiquitous across species ranging from viruses to mammals. Important advances …
Targeting circular RNAs as a therapeutic approach: current strategies and challenges
Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
CircRNA in cancer: fundamental mechanism and clinical potential
Abstract Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are
formed in a circular conformation via non-canonical splicing or back-splicing events …
formed in a circular conformation via non-canonical splicing or back-splicing events …
The expanding regulatory mechanisms and cellular functions of circular RNAs
LL Chen - Nature reviews Molecular cell biology, 2020 - nature.com
Many protein-coding genes in higher eukaryotes can produce circular RNAs (circRNAs)
through back-splicing of exons. CircRNAs differ from mRNAs in their production, structure …
through back-splicing of exons. CircRNAs differ from mRNAs in their production, structure …
[HTML][HTML] miRNA-based biomarkers, therapies, and resistance in Cancer
B He, Z Zhao, Q Cai, Y Zhang, P Zhang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …
size, play important roles in gene regulation, and their dysregulation is implicated in human …