Several specific conclusions can be drawn from these studies: 1. IL-4 is required for the
generation of both primary polyclonal and secondary antigen-specific IgE responses in vivo …

Publisher Summary Because cytokine functions are complex and overlapping, the
development of precise, monospecific bioassays, and enzyme-linked immunosorbent …

Interleukin 5 (IL-5) has been suggested to be involved in the growth and differentiation of B
cells and eosinophils. Especially, Ly-1+ B cells, which have been considered to produce …

TRF has originally been defined as a T-cell-derived lymphokine that triggers activated B
cells for a terminal differentiation into Ig-secreting cells. HPLC-purified TRF from Sup of a …

Certain infections, like that with the human immunodeficiency virus‐1, deplete vitamin A, and
when vitamin A levels are low, immune dysfunctions establish susceptibility to further …

Publisher Summary The chapter summarizes advances in interleukin-5 (IL-5) and IL-soluble
receptor (IL-SR) research in the study of structure, physiologic functions, and the unique …

Publisher Summary This chapter discusses the interactions between T and B cells and the
role of accessory cells and cytokines in the generation of specific antibody responses. The …

The mechanisms of immune response following yellow fever (YF-17DD) vaccination are still
poorly understood. In this study, we have performed a longitudinal investigation (days 0, 7 …

The availability of large quantities of highly purified recombinant interleukin 11 (rhuIL-11)
has allowed us to investigate the effects of rhuIL-11 on sheep red blood cell (SRBC)-specific …

The role of lymphocytes in the pathogenesis of periodontitis has been in question since the
early 1900s, following light microscopic observations that these cells comprise a major …