Life stress and health: A review of conceptual issues and recent findings

GM Slavich - Teaching of Psychology, 2016 - journals.sagepub.com
Life stress is a central construct in many models of human health and disease. The present
article reviews research on stress and health, with a focus on (a) how life stress has been …

Expression quantitative trait loci: present and future

AC Nica, ET Dermitzakis - Philosophical Transactions of …, 2013 - royalsocietypublishing.org
The last few years have seen the development of large efforts for the analysis of genome
function, especially in the context of genome variation. One of the most prominent directions …

The emerging field of human social genomics

GM Slavich, SW Cole - Clinical psychological science, 2013 - journals.sagepub.com
Although we generally experience our bodies as being biologically stable across time and
situations, an emerging field of research is demonstrating that external social conditions …

Mapping complex disease traits with global gene expression

W Cookson, L Liang, G Abecasis, M Moffatt… - Nature Reviews …, 2009 - nature.com
Variation in gene expression is an important mechanism underlying susceptibility to
complex disease. The simultaneous genome-wide assay of gene expression and genetic …

Revealing the architecture of gene regulation: the promise of eQTL studies

Y Gilad, SA Rifkin, JK Pritchard - Trends in genetics, 2008 - cell.com
Expression quantitative trait loci (eQTL) mapping studies have become a widely used tool
for identifying genetic variants that affect gene regulation. In these studies, expression levels …

Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytes

SW Cole, LC Hawkley, JMG Arevalo… - Proceedings of the …, 2011 - National Acad Sciences
To clarify the biological rationale for social regulation of gene expression, this study sought
to identify the specific immune cell types that are transcriptionally sensitive to subjective …

High-resolution mapping of expression-QTLs yields insight into human gene regulation

JB Veyrieras, S Kudaravalli, SY Kim… - PLoS …, 2008 - journals.plos.org
Recent studies of the HapMap lymphoblastoid cell lines have identified large numbers of
quantitative trait loci for gene expression (eQTLs). Reanalyzing these data using a novel …

Social regulation of human gene expression: mechanisms and implications for public health

SW Cole - American journal of public health, 2013 - ajph.aphapublications.org
Recent analyses have discovered broad alterations in the expression of human genes
across different social environments. The emerging field of social genomics has begun to …

Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk

CP Wild, A Scalbert, Z Herceg - Environmental and molecular …, 2013 - Wiley Online Library
Advances in laboratory sciences offer much in the challenge to unravel the complex etiology
of cancer and to therefore provide an evidence‐base for prevention. One area where …

The genetic architecture of adaptations to high altitude in Ethiopia

G Alkorta-Aranburu, CM Beall, DB Witonsky… - PLoS …, 2012 - journals.plos.org
Although hypoxia is a major stress on physiological processes, several human populations
have survived for millennia at high altitudes, suggesting that they have adapted to hypoxic …