How mass spectrometric interrogation of MHC class I ligandomes has advanced our understanding of immune responses to viruses
N Ternette, E Adamopoulou, AW Purcell - Seminars in Immunology, 2023 - Elsevier
The T cell receptor (TCR) recognises peptide antigens presented by major histocompatibility
complexes (MHC) presented on the surface of cells, and can, in response, elicit an immune …
complexes (MHC) presented on the surface of cells, and can, in response, elicit an immune …
Recent advances in immunopeptidomic-based tumor neoantigen discovery
W Meng, RD Schreiber, CF Lichti - Advances in Immunology, 2023 - Elsevier
The role of aberrantly expressed proteins in tumors in driving immune-mediated control of
cancer has been well documented for more than five decades. Today, we know that both …
cancer has been well documented for more than five decades. Today, we know that both …
Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting
X Wan, K Wisskirchen, T Jin, L Yang, X Wang… - Clinical and Molecular …, 2024 - e-cmh.org
Methods Good Manufacturing Practice-grade manufactured cells were assessed for off-
target reactivity and functionality against hepatoma cells. Subsequently, a patient with …
target reactivity and functionality against hepatoma cells. Subsequently, a patient with …
[HTML][HTML] Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting
X Wan, K Wisskirchen, T Jin, L Yang… - Clinical and …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Aims Hepatitis B virus (HBV)-DNA integration in HBV-related hepatocellular
carcinoma (HBV-HCC) can be targeted by HBV-specific T cells. SCG101 is an autologous …
carcinoma (HBV-HCC) can be targeted by HBV-specific T cells. SCG101 is an autologous …
Mass Spectrometry-Based Discovery of Tumor Antigens for Cancer Immunotherapy
W Meng - 2023 - search.proquest.com
The immune system plays an essential role in cancer evolution and cancer treatment. One of
the major mechanisms of immune-mediated tumor rejection is the recognition of tumor …
the major mechanisms of immune-mediated tumor rejection is the recognition of tumor …
A critical review of the prospects and challenges of Hepatitis B therapeutic vaccines
Hepatitis B therapeutic vaccines hold great promise in the treatment of chronic Hepatitis B
virus (HBV) infection. However, like any medical intervention, they also face certain …
virus (HBV) infection. However, like any medical intervention, they also face certain …