Once viewed as part of the “dark matter” of genome, long noncoding RNAs (lncRNAs), which
are mRNA-like but lack open reading frames, have emerged as an integral part of the …

Next-generation sequencing (NGS) technologies and data have revolutionized cancer
research and are increasingly being deployed to guide clinicians in treatment decision …

Long intergenic noncoding RNAs (lincRNAs) have been gradually identified to be functional
in a variety of different mechanisms associating with development and epigenetic regulation …

Diabetic nephropathy is an important microvascular complication of diabetes, and the
incidence of end-stage renal disease caused by it are rising annually. Long non-coding …

Macrophages in the tumor microenvironment are causally linked with prostate cancer
development and progression, yet little is known about their composition in neoplastic …

Recent studies have indicated that long noncoding RNAs (lncRNAs) play important roles in
multiple processes, such as epigenetic regulation, gene expression regulation …

The cases of inflammatory bowel disease (IBD) are increasing rapidly around the world. Due
to the multifactorial causes of IBD, there is an urgent need to understand the pathogenesis of …

Diabetic kidney disease (DKD) has surpassed chronic glomerulonephritis as the leading
cause of end-stage renal disease. Previously, we showed that early growth response protein …

Background Intron-derived long noncoding RNAs with snoRNA ends (sno-lncRNAs) are
highly expressed from the imprinted Prader-Willi syndrome (PWS) region on human …

Background: Studies have shown that long noncoding RNAs (lncRNAs) are involved in the
development and progression of many types of cancer. However, the mechanisms by which …