Circulating endocannabinoids: from whence do they come and where are they going?

CJ Hillard - Neuropsychopharmacology, 2018 - nature.com
The goal of this review is to summarize studies in which concentrations of circulating
endocannabinoids in humans have been examined in relationship to physiological …

Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation

SB Raut, PA Marathe, L van Eijk, R Eri… - Pharmacology & …, 2022 - Elsevier
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training

M Morena, B Roozendaal, V Trezza… - Proceedings of the …, 2014 - National Acad Sciences
Previous studies have provided extensive evidence that administration of cannabinoid drugs
after training modulates the consolidation of memory for an aversive experience. The …

The basic science of cannabinoids

A Sideris, J Lauzadis, M Kaczocha - Anesthesia & Analgesia, 2024 - journals.lww.com
The cannabis plant has been used for centuries to manage the symptoms of various
ailments including pain. Hundreds of chemical compounds have been identified and …

Enhancing endocannabinoid neurotransmission augments the efficacy of extinction training and ameliorates traumatic stress-induced behavioral alterations in rats

M Morena, A Berardi, P Colucci, M Palmery… - …, 2018 - nature.com
Exposure to a traumatic event may result in the development of post-traumatic stress
disorder (PTSD). Endocannabinoids are crucial modulators of the stress response, interfere …

The endocannabinoid system and Post Traumatic Stress Disorder (PTSD): From preclinical findings to innovative therapeutic approaches in clinical settings

A Berardi, G Schelling, P Campolongo - Pharmacological research, 2016 - Elsevier
Abstract Post-Traumatic Stress Disorder (PTSD) is a psychiatric chronic disease developing
in individuals after the experience of an intense and life-threatening traumatic event. The …

The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD)

V Trezza, P Campolongo - Frontiers in behavioral neuroscience, 2013 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a psychiatric disorder of significant prevalence and
morbidity, whose pathogenesis relies on paradoxical changes of emotional memory …

Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome

M Qin, Z Zeidler, K Moulton, L Krych, Z Xia… - Behavioural Brain …, 2015 - Elsevier
Silencing the gene FMR1 in fragile X syndrome (FXS) with consequent loss of its protein
product, FMRP, results in intellectual disability, hyperactivity, anxiety, seizure disorders, and …

Targeting the endocannabinoid system to treat anxiety-related disorders

N Korem, TM Zer-Aviv, E Ganon-Elazar… - Journal of basic and …, 2016 - degruyter.com
The endocannabinoid system plays an important role in the control of emotions, and its
dysregulation has been implicated in several psychiatric disorders. The most common self …

Effects of ketamine, dexmedetomidine and propofol anesthesia on emotional memory consolidation in rats: consequences for the development of post-traumatic stress …

M Morena, A Berardi, A Peloso, D Valeri… - Behavioural brain …, 2017 - Elsevier
Abstract Intensive Care Unit (ICU) or emergency care patients, exposed to traumatic events,
are at increased risk for Post-Traumatic Stress Disorder (PTSD) development. Commonly …