Accumulation of advanced glycation end products (AGEs) on nucleotides, lipids, and
peptides/proteins are an inevitable component of the aging process in all eukaryotic …

Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

Glycation is a non-enzymatic process involving the reaction of reducing sugars or reactive
oxoaldehyde with proteins, lipids or nucleic acids, which results in the formation of advanced …

Recently, it has been proposed that the receptor for advanced glycation end-products
(RAGE) plays a crucial role in damaging cellular processes, such as neuroinflammation …

Advanced glycation end products (AGEs) are produced through the non enzymatic glycation
and oxidation of proteins, lipids and nucleic acids. Enhanced formation of AGEs occurs …

Background Emphysema is a key contributor to airflow limitation in chronic obstructive
pulmonary disease (COPD) and can be quantified using CT scanning. We investigated the …

Diabetes is characterized by accelerated atherosclerosis with widely distributed vascular
lesions. An important mechanism by which hyperglycaemia contributes to vascular injury is …

In this study, we investigated the preventive effects of carnosic acid (CA) as a major
bioactive component in rosemary extract (RE) on high-fat-diet-induced obesity and …

Context Prediabetes is associated with subclinical cardiac changes associated with heart
failure development. Objective We investigated diastolic function and its association with …

The receptor for advanced glycation end products (RAGE) is expressed in the heart in
cardiomyocytes, vascular cells, fibroblasts, and in infiltrating inflammatory cells. Experiments …