Biological activity, quantitative structure–activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs

I Miladiyah, J Jumina, SM Haryana… - Drug design …, 2018 - Taylor & Francis
Background Xanthone derivatives have a wide range of pharmacological activities, such as
those involving antibacterial, antiviral, antimalarial, anthelmintic, anti-inflammatory …

[HTML][HTML] In silico study of essential oil of Bambusa vulgaris leaves as an anti beta-lactamase compound

PW Anggini, SA Amanina, SR Asyura… - Molecular and Cellular …, 2022 - cellbiopharm.com
Background: Klebsiella pneumoniae is known as an extended spectrum beta (β)-lactamases
(ESBLs)-producing bacteria, which produces enzymes that cause resistance to β-lactam …

Molecular docking of the terpenes in gorgonian corals to COX-2 and iNOS enzymes as anti-inflammatory

FJ Kelutur, NM Saptarini… - Letters in Drug …, 2022 - ingentaconnect.com
Background: Because the inflammatory pathway is triggered by the enzymes
cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), inhibitors, such as …

[PDF][PDF] In silico molecular docking of xanthone derivatives as cyclooxygenase-2 inhibitor agents

I Miladiyah, J Jumina, SM Haryana… - Int J Pharm Pharm Sci, 2017 - academia.edu
Objective: To demonstrate the potential ofdifferent xanthone derivatives as cyclooxygenase-
2 (COX-2) inhibitor agents and their selectivity against cycloooxygenase-1 (COX-1) and …

Exploring the Antidiarrheal Properties of Papaya Leaf: Insights In Vivo Study in Mice‐Model and In Silico Analysis at M3 Muscarinic Acetylcholine Receptor …

NM Saptarini, FJ Kelutur, MJAT Corpuz - Scientifica, 2024 - Wiley Online Library
Diarrhea caused by gut motility involves 5‐HT3 serotonin receptor (5‐HT3R) antagonist, M3
muscarinic acetylcholine receptor (M3‐AchR), and H1 histamine receptor (H1R) via their …

Synthesis and molecular docking of isonicotinohydrazide derivatives as anti-tuberculosis candidates

R Ruswanto, R Mardianingrum, T Lestari… - Malaysian Journal of …, 2019 - mjfas.utm.my
Tuberculosis (TB) is a chronic disease as a result of Mycobacterium tuberculosis. It can
affect all age groups, and hence, is a global health problem that causes the death of millions …

In silico study of fucoxanthin as a tumor cytotoxic agent

HI Januar, AS Dewi, E Marraskuranto… - Journal of Pharmacy …, 2012 - journals.lww.com
Background: Fucoxanthin is a potential tumor cytotoxic compound. However, mechanisms
underlying the activities are unclear. Aim: This in silico study aimed to predict the main …

Anti-breast cancer activities from the sea fan (Gorgonia mariae): Pharmacophore screening and in-silico molecular docking study

FJ Kelutur - AIP Conference Proceedings, 2023 - pubs.aip.org
Sea fan, a type of gorgonian coral, originating from Maluku, Indonesia, which local people
have used as medicinal ingredients for generations. Gorgonian has anti-inflammatory, anti …

Sterol Constituents of Sea Fan (Gorgonia mariae) as Potential Candidates of MPro Protein SARS-CoV-2 Inhibitor: in silico Study

FJ Kelutur - Indonesian Journal of Chemical Research, 2022 - ojs3.unpatti.ac.id
Ethnobotanically, sea fan was a group of gorgonian coral that have used the Maluku people
as medicinal ingredients with secondary metabolites containing sterols, terpenoids, and …

[PDF][PDF] In vitro and in silico evaluation of xanthine oxidase inhibitory activity of quercetin contained in Sonchus arvensis leaf extract

R Hendriani, N Nursamsiar… - Asian Journal of …, 2017 - academia.edu
Objective: The aim of the present study was to examine the inhibiting effects of quercetin
contained in Sonchus arvensis leaf extract on the activity of xanthine oxidase, an essential …