[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
[HTML][HTML] Cognitive impact of COVID-19: looking beyond the short term
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …
Cerebral amyloid angiopathy and Alzheimer disease—one peptide, two pathways
SM Greenberg, BJ Bacskai… - Nature Reviews …, 2020 - nature.com
The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …
Early postmortem brain MRI findings in COVID-19 non-survivors
T Coolen, V Lolli, N Sadeghi, A Rovai, N Trotta… - Neurology, 2020 - AAN Enterprises
Objectives The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
considered to have potential neuroinvasiveness that might lead to acute brain disorders or …
considered to have potential neuroinvasiveness that might lead to acute brain disorders or …
[HTML][HTML] Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management
MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021 - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …
cardiovascular risk factors is currently the most effective approach to prevent cognitive …
Understanding the role of the perivascular space in cerebral small vessel disease
R Brown, H Benveniste, SE Black… - Cardiovascular …, 2018 - academic.oup.com
Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …
[HTML][HTML] Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance
imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia …
imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia …
Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex
Perivascular spaces (PVS) are compartments surrounding cerebral blood vessels that
become visible on MRI when enlarged. Enlarged PVS (EPVS) are commonly seen in …
become visible on MRI when enlarged. Enlarged PVS (EPVS) are commonly seen in …
[HTML][HTML] Perivascular spaces and their role in neuroinflammation
It is uncontested that perivascular spaces play critical roles in maintaining homeostasis and
priming neuroinflammation. However, despite more than a century of intense research on …
priming neuroinflammation. However, despite more than a century of intense research on …
Neuroimaging in dementia: more than typical Alzheimer disease
Alzheimer disease (AD) is the most common cause of dementia. The prevailing theory of the
underlying pathology assumes amyloid accumulation followed by tau protein aggregation …
underlying pathology assumes amyloid accumulation followed by tau protein aggregation …