Large-scale regeneration in the adult central nervous system is a unique capacity of
salamanders among tetrapods. Salamanders can replace neuronal populations, repair …

Conventional mammalian models of neurodegeneration are often limited by futile
axonogenesis with minimal functional recuperation of severed neurons. The emergence of …

Background Previous studies have suggested that macrophages are present during lens
regeneration in newts, but their role in the process is yet to be elucidated. Methods Here we …

The overall bauplan of the tetrapod brain is highly conserved, yet significant variations exist
among species in terms of brain size, structural composition and cellular diversity …

Background Although tissue clearing and subsequent whole-brain imaging is now possible,
standard protocols need to be adjusted to the innate properties of each specific tissue for …

Electroporation is an increasingly common technique used for exogenous gene expression
in live animals, but protocols are largely limited to traditional laboratory organisms. The goal …

In order to understand the biological processes underlying dopaminergic neurons (DpN)
regeneration in a 6-hydroxydopamine (6-OHDA)-induced adult zebrafish-based Parkinson's …

Parkinson's disease (PD) is the second most common neurodegenerative disease. The
etiology of PD remains an enigma with no available disease modifying treatment or cure …