Remnant cholesterol, but not low‐density lipoprotein cholesterol, is associated with intra‐pancreatic fat deposition

L Skudder‐Hill, IR Sequeira‐Bisson… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To investigate the associations of components of the lipid panel (and its derivatives)
with intra‐pancreatic fat deposition (IPFD). Methods All participants underwent abdominal …

Effects of liraglutide on intrapancreatic fat deposition in patients with type 2 diabetes

T Kuriyama, C Ishibashi, J Kozawa, MY Baden… - Clinical Nutrition …, 2024 - Elsevier
Background & aims Ectopic fat deposition is associated with worsening of glycemic control.
This study was conducted to determine whether liraglutide reduces ectopic fat deposition …

Intra‐pancreatic fat is associated with continuous glucose monitoring metrics

Y Liu, W Kimita, X Shamaitijiang… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim To investigate the relationship of fat in the pancreas with time spent in different
glycaemic ranges. Methods Abdominal magnetic resonance imaging at 3.0 Tesla was used …

Gut microbiota profiles in two New Zealand cohorts with overweight and prediabetes: a Tū Ora/PREVIEW comparative study

A Mathrani, LW Lu, IR Sequeira-Bisson… - Frontiers in …, 2023 - frontiersin.org
Obesity-related metabolic diseases such as type 2 diabetes (T2D) are major global health
issues, affecting hundreds of millions of people worldwide. The underlying factors are both …

Effect of a Higher-Protein Nut versus Higher-Carbohydrate Cereal Enriched Diet on the Gut Microbiomes of Chinese Participants with Overweight and …

S Faraj, IR Sequeira-Bisson, L Lu, JL Miles-Chan… - Nutrients, 2024 - mdpi.com
Global increases in metabolic disorders such as type 2 diabetes (T2D), especially within
Asian populations, highlight the need for novel approaches to dietary intervention. The Tū …

Circulatory miRNAs as Correlates of Elevated Intra-Pancreatic Fat Deposition in a Mixed Ethnic Female Cohort: The TOFI_Asia Study

F Ramzan, IR Sequeira-Bisson, LW Lu… - International Journal of …, 2023 - mdpi.com
Ectopic lipid accumulation, including intra-pancreatic fat deposition (IPFD), exacerbates type
2 diabetes risk in susceptible individuals. Dysregulated circulating microRNAs (miRNAs) …

[HTML][HTML] Intra-pancreatic fat is associated with high circulating glucagon and GLP-1 concentrations following whey protein ingestion in overweight women with …

JJ Lim, IR Sequeira-Bisson, WCY Yip, LW Lu… - Diabetes Research and …, 2024 - Elsevier
Aim Intra-pancreatic fat deposition (IPFD) while hypothesised to impair beta-cell function, its
impact on alpha-cells remains unclear. We evaluated the association between IPFD and …

[HTML][HTML] When Being Lean Is Not Enough: The Metabolically Unhealthy Normal Weight Phenotype and Cardiometabolic Disease

D Park, MJ Shin, F Magkos - CardioMetabolic Syndrome Journal, 2024 - e-cmsj.org
Conventional wisdom associates increased body weight with suboptimal health. However, it
has become apparent in recent years that excess weight and total body fat do not …

Automated image analysis method to detect and quantify fat cell infiltration in hematoxylin and eosin stained human pancreas histology images

RR Naik, A Rajan, N Kalita - bioRxiv, 2021 - biorxiv.org
Fatty infiltration in pancreas leading to steatosis is a major risk factor in pancreas
transplantation. Hematoxylin and eosin (H and E) is one of the common histological staining …

Exploring the relationship between pancreatic fat and insulin secretion in overweight or obese women without type 2 diabetes mellitus: A preliminary investigation of …

IR Sequeira, W Yip, LW Lu, Y Jiang, R Murphy… - PLoS …, 2022 - journals.plos.org
Objective While there is an emerging role of pancreatic fat in the aetiology of type 2 diabetes
mellitus (T2DM), its impact on the associated decrease in insulin secretion remains …